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01
Lead carboxylates passivation for meter-scale perovskite solar modules
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10994-7 Lead carboxylates passivation for meter-scale perovskite solar modulesDongdong Xu
02
Reply to: Pre-clinical data interpretation requires clinical context
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10773-4 Reply to: Pre-clinical data interpretation requires clinical contextSean P. Pitroda
03
Pre-clinical data interpretation requires clinical context
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10774-3 Pre-clinical data interpretation requires clinical contextR. Muirhead
04
Giant balloon gives rise to new view of the Milky Way’s centre
Nature, Published online: 12 August 2026; doi:10.1038/d41586-026-02463-y Airborne camera gathers data about the high-energy particles emanating from the core of our Galaxy.Nature, Published online: 2026-08-12; | doi:10.1038/d41586-026-02463-y
05
Rattlesnakes’ own anti-venom could protect humans too
Nature, Published online: 12 August 2026; doi:10.1038/d41586-026-02461-0 A mixture of proteins in snake blood can prevent the death of mice injected with an otherwise lethal dose of venom.Nature, Published online: 2026-08-12; | doi:10.1038/d41586-026-02461-0
06
The probiotic bacteria engineered to treat diabetes
Nature, Published online: 12 August 2026; doi:10.1038/d41586-026-02521-5 Genetically modified bacteria lower high blood-sugar in animal trials — plus, how to watch a solar eclipse safely.Nick Petrić Howe
07
Dataset artefacts can partially drive the measured decline in disruption
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10787-y Dataset artefacts can partially drive the measured decline in disruptionVincent Holst
08
Reply to: Dataset artefacts can partially drive the measured decline in disruption
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10788-x Reply to: Dataset artefacts can partially drive the measured decline in disruptionMichael Park
09
Agentic profiles for effective AI governance
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10805-z A framework comprising four dimensions—autonomy, efficacy, goal complexity and generality—is proposed for characterizing AI agents, supporting the construction of agentic profiles for the effective governance of different AI agents.Atoosa Kasirzadeh
10
Glucose-responsive probiotics for glycaemic modulation in mice and monkeys
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10909-6 Engineered probiotics equipped with a synthetic glucose-responsive circuit transiently colonize the gut and secrete therapeutic factors when glucose levels increase, enabling safe, oral, sense-and-respond control of diabetes in mouse and primate models.Ningzi Guan
11
Temporal uncoupling of radial glia lineage progression in cortical organoids
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10916-7 RGP lineage tracing in stem-cell-derived organoids shows highly plastic proliferation and reduced clonal neuronal diversity, indicating that missing non-cell-autonomous niche cues are essential for faithful temporal control of cortical lineage progression.Melissa Stouffer
12
Shared principles of human and bacterial antiviral immunity
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10756-5 The Review describes shared ancient, conserved mechanisms between human antiviral immunity and bacterial anti-phage systems, outlining universal principles of pathogen sensing, signalling and effector function that reveal common rules governing host–virus interactions across life.Philip J. Kranzusch
13
Cascading continental-scale floods across Europe in 1342–1343
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10888-8 Tracing cascading continental-scale medieval megafloods across Europe indicates that current flood management is unprepared for such sequences, highlighting the urgent need for proactive flood risk management strategies that account for unusual series of extreme flood events.Andrea Kiss
14
Rb-driven transcription limits its tumour-suppressive effects in breast cancer
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10886-w CDK4/6 inhibition redirects Rb chromatin occupancy to activate oestrogen-responsive genes, counteracting its own ability to maintain therapeutic cell-cycle arrest.April C. Watt
15
Procognitive restoration of PV neuron plasticity in neurodevelopmental disorders
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10907-8 Expression of Meis2 in hippocampal parvalbumin-expressing interneurons in an adult mouse model of neurodevelopmental disorders rescues experience-dependent plasticity, improves memory and network function and suppresses seizures.Yu-Tzu Shih
16
A gas-enshrouded and gas-reddened black hole at cosmic dawn
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10846-4 Observations of an unusual cosmic-dawn source illuminate how early supermassive black holes may have grown rapidly in a gas-enshrouded state; such enshrouded black holes may lie at the heart of the 'little red dots'.Rohan P. Naidu
17
Towards an equitable future of global photovoltaic waste recycling
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10905-w Global photovoltaic waste will reach 297–402 million tonnes by 2060, and regionally adapted recycling strategies and international cooperation will be needed to provide equitable and scalable PV waste circularity.Chen Wang
18
Luminescent-reaction-enabled super-resolution imaging
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10889-7 A new chemistry-based super-resolution imaging framework is described, enabling 3D, laser-free, highly sensitive and ultralong-term imaging of live cells which overcomes the limitations in spatiotemporal resolution associated with reaction-based imaging methods.Wenxin Zhu
19
Degree-of-polarization modulation for high-dimensional optical computing
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10891-z By engineering the statistics of light at the micrometre scale using phase-only spatial light modulators, both the state and degree of polarization become spatially programmable, enabling direct encoding of information in a high-dimensional space.Alessandro Petrini
20
Neural basis of compositional control
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10896-8 Behaviour of human participants in a prey-pursuit task reflects dynamic blending of goal-specific control policies, with hippocampus estimating latent states, anterior cingulate cortex orchestrating policy switches and orbitofrontal cortex supplying value-based contextualization rather than driving continuous policy updating.Assia Chericoni
21
Structural mechanism governing the directionality of bridge recombination
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10903-y Cryo-electron microscopy structures show how IS621 bridge recombinase mediates DNA excision, explaining its natural preference for insertion and informing the design of programmable bridge-editing technologies.Masahiro Hiraizumi
22
Species intraspecific variation drives tropical forest drought resistance
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10870-4 Substantial intraspecific variation, together with species turnover, drives coordinated shifts in drought resistance such as increased embolism resistance and wider stomatal safety margins in drier forests.Chris M. Smith-Martin
23
Numerous bow shocks in the outer Helix Nebula
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10724-z Shocks in the eastern outskirts of the Helix Nebula, detected in Hα emission with the MOTHRA telescope, provide evidence for the recycling of fragmented stellar ejecta into the surrounding gas.Pieter van Dokkum
24
Maternal influences on infant gut microbiome and health
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10922-9 The maternal gut microbiome is a predictor of infant eczema.Trishla Sinha
25
Evidence for the first globular cluster stellar stream beyond the Milky Way
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10878-w Deep Hubble Space Telescope imaging of the ultra-diffuse galaxy UGC 9050-Dw1 reveals an extragalactic globular cluster stream, with analysis and modelling probing the rich dark matter content of the host galaxy.Julie Kiel Holm
26
Heterogeneous climatic controls on tropical-forest biomass
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10880-2 An analysis of the relationships between aboveground biomass and various climatic factors in three major regions of tropical forest shows that understanding the complex interactions between climate, topography and soils is crucial to predict how climate change will affect carbon storage capacity.Matheus Henrique Nunes
27
Superconducting 2D cuprate with a single CuO<sub>2</sub> plane
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10857-1 A high-quality, pristine monolayer cuprate superconductor with a single CuO2 plane is fabricated and used to identify two quantum critical phenomena emerging between the Mott insulating phase and the superconducting phase.Hengsheng Luo
28
In vivo genome-wide CRISPR screens of human T cells in solid tumours
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10906-9 An in vivo model that is able to recover human T cells from solid tumours can identify targets to help improve CAR T cell antitumour activity.Qi Liu
29
Biomarkers of nivolumab benefit in resectable non-small cell lung cancer
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10925-6 Potential predictive biomarkers of perioperative nivolumab therapy benefit in non-small cell lung cancer are identified from evaluable participants in the CheckMate 77T trial.Tina Cascone
30
How the human brain can pursue two goals at the same time
Nature, Published online: 12 August 2026; doi:10.1038/d41586-026-02395-7 In the natural world, an animal can blend strategies so it can advance towards several goals at the same time. An engineering approach called control theory was used to infer people’s goals while they played a simple video game, and showed how three brain regions work together to implement goal blending.Nature, Published online: 2026-08-12; | doi:10.1038/d41586-026-02395-7

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