Nature Neuroscience, Published online: 05 August 2026; doi:10.1038/s41593-026-02388-9 The authors present a dense connectomic reconstruction of a 0.1 mm3 hippocampal CA3 volume and reveal spatial gradients, high convergence and cell-type-selective feedforward inhibition of inputs to pyramidal cells.Zhihao Zheng
Nature Neuroscience, Published online: 05 August 2026; doi:10.1038/s41593-026-02379-w This study shows that GPCR-based norepinephrine and dopamine sensors display crosstalk in several brain areas. Relative innervation densities determine the extent of crosstalk, and loss-of-function controls are required to interpret sensor signals.Ricardo C. López
Nature Neuroscience, Published online: 04 August 2026; doi:10.1038/s41593-026-02382-1 Compositionality exists on a continuum of increasing complexity rather than as a binary trait. Studying its implementation in simpler biological and artificial systems is the most tractable path toward understanding its role in general intelligence.Reidar Riveland
Nature Neuroscience, Published online: 04 August 2026; doi:10.1038/s41593-026-02367-0 Klimmt, Cardoso Gonçalves et al. developed a reproducible human three-dimensional brain tissue model with neurons, astrocytes and microglia, replicating in-vivo-like maturation and enabling the study of Alzheimer’s disease-relevant perturbations and drug responses.Julien Klimmt
Nature Neuroscience, Published online: 03 August 2026; doi:10.1038/s41593-026-02425-7 Publisher Correction: Duration between rewards controls the rate of behavioral and dopaminergic learningDennis A. Burke
