
Nature · 实时热榜
- 01AI agents are checking the scientific literature — and spotting decades-old errors
Nature, Published online: 06 August 2026; doi:10.1038/d41586-026-02235-8 The technology is proving adept at finding faults in decades-old papers and reference databases.
最高第 3 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 02How a steady drip-drip can erode the hardest stone
Nature, Published online: 06 August 2026; doi:10.1038/d41586-026-02360-4 Measuring the deformation of a surface hit by a falling droplet offers insights into water’s erosive power.
最高第 2 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 03Pumas are drivers’ guardian angels
Nature, Published online: 06 August 2026; doi:10.1038/d41586-026-02429-0 Vehicles are less likely to smash into deer on the road where the big cats are on patrol.
最高第 1 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 04<b>Junk plastic turns into high-value commodity with chemistry trick</b>
Nature, Published online: 05 August 2026; doi:10.1038/d41586-026-02445-0 Researchers untangle the chemistry behind turning PVC into high-grade motor lubricant — plus, how engineered yeast can help make a cancer drug.
最高第 7 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 05Virus reactivation in acute and long COVID-19
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10740-z Chronic reactivation of distinct herpesviruses and anelloviruses occur during acute and long COVID-19, and track with disease severity, inflammation and outcomes, revealing immune signatures with prognostic potential.
最高第 21 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 06An expanded codebook of human transcription factor DNA-binding specificity
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10798-9 Results from a panel of assays that analyse different aspects of DNA sequence specificity reveal more than 100 new motifs to aid the characterization of putative human transcription factors.
最高第 8 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 07A compendium of next-generation patient-derived models for diverse cancers
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10806-y The international collaboration of the Human Cancer Models Initiative presents a comprehensive resource of next-generation cancer models from 2,780 donors with 25 cancer types and integrated tumour–model genomic, transcriptomic and epigenomic analyses.
最高第 18 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 08An entangling gate for dual-rail erasure qubits
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10822-y A fast, low-error entangling gate for dual-rail cavity erasure qubits preserves a strong error hierarchy, advancing scalable quantum error correction with substantially improved fault-tolerant performance.
最高第 15 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 09A tumour-derived organoid biobank maps cancer gene dependencies
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10830-y A clinically annotated multi-omic organoid resource with matched tumour samples from 256 patients across 5 cancers maps gene dependencies, reveals subtype-specific vulnerabilities and uncovers treatment-driven changes, expanding mechanistic insight and models for precision oncology.
最高第 25 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 10A dependency map enhanced with next-generation 3D cancer models
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10843-7 Integration of genome-scale CRISPR screening data from traditional cell lines and next-generation cancer models expands the representation of tumour subtypes and genomic alterations in The Cancer Dependency Map.
最高第 13 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 11Antigen presentation by CD40<sup>+</sup>MHC-II<sup>+</sup> astrocytes promotes CNS autoimmunity
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10860-6 Astrocytes promote central nervous system (CNS) immunity through antigen presentation and activation of CD40 in astrocytes by CD40L expressed by CD4+ T cells in a model of experimental autoimmune encephalomyelitis.
最高第 19 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 12Uncovering the mechanism of female restitution in sugarcane hybrids
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10863-3 Female restitution in interspecific sugarcane hybrids between Saccharum officinarum and Saccharum spontaneum arises from second division restitution, as haplotype-resolved F1 genomes reveal duplicated, partially recombined maternal chromatids and distinctive recombination signatures, resolving its meiotic mechanism and enabling breeding strategies to accelerate crop improvement.
最高第 22 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 13Encapsulation epitaxy of air-stable 2D superconductors for quantum circuits
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10865-1 An ‘encapsulation epitaxy’ mechanism is used to grow air-stable, two-dimensional superconducting films at the interface of a 2D–3D hybrid substrate, holding promise for use in fabrication of superconducting quantum circuitry.
最高第 16 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 14Upcycling of polyvinyl chloride into polyalphaolefin lubricants
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10867-z A mild chemical process upcycles polyvinyl chloride waste into polyalphaolefin lubricants with tunable properties, offering an economical route to plastic recycling and improved carbon circularity.
最高第 14 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 15Ubiquitous Kelvin–Helmholtz instabilities driving plasma mixing on the Sun
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10871-3 High-spatial-resolution observations of the solar photosphere reveal a far more complex and dynamic solar scene than previously observed and show that ubiquitous Kelvin–Helmholtz instabilities drive plasma mixing on the Sun.
最高第 9 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 16Amygdala astrocyte primary cilium mechanisms contribute to stress behaviours
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10874-0 Amygdala astrocyte primary cilia are disrupted during stress, and their restoration leads to improvements in stress-related behaviour in mice.
最高第 12 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 17Pseudogap in a Fermi–Hubbard quantum simulator
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10875-z A cold-atom quantum simulator reveals the pseudogap metallic state in the Hubbard model, mapping its phase diagram and advancing understanding of doped Mott insulators and high-temperature superconductivity.
最高第 23 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 18Stimulation modulates gene-linked cell assemblies in the human brain
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10879-9 Stimulation of human cortex reorganizes neural assemblies and induces cell-type-specific gene regulatory programs, establishing an ex vivo framework that links stimulation parameters to circuit and transcriptional responses for designing targeted neuromodulatory therapies.
最高第 17 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 19In situ particle-to-fibre transformation of hydrogels for 3D printing
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10883-z A three-dimensional printing method transforms hydrogel particles into aligned microfibres during extrusion, creating structural anisotropy to accelerate muscle tissue regeneration.
最高第 11 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 20The Virtual Tissues foundation model resolves spatial proteomics across scales
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10884-y Virtual Tissues (VirTues), a foundation model for spatial proteomics that captures tissue organization across scales, supports marker reconstruction, cell segmentation and typing, niche annotation, spatial biomarker discovery and patient stratification across heterogeneous panels and datasets.
最高第 20 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 21ZFP36L2 orchestrates stress-adaptive plasticity in regeneration and cancer
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10890-0 The RNA-binding protein ZFP36L2 mediates stress-adaptive plasticity in intestinal regeneration and colorectal cancer metastasis.
最高第 10 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 22Membranolytic peptide programs immunogenic cell death for cancer therapy
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10899-5 The synthetic-acid-responsive membranolytic peptide aMPC16-CA50 induces immunogenic membranolytic cell death in tumour cells, robustly potentiating immune checkpoint blockade therapy.
最高第 24 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 23Publisher Correction: Progressive plasticity during colorectal cancer metastasis
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10963-0 Publisher Correction: Progressive plasticity during colorectal cancer metastasis
最高第 5 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 24Thermally evaporated perovskite/silicon tandems via formamidinium eutectic
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10970-1 Thermally evaporated perovskite/silicon tandems via formamidinium eutectic
最高第 4 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 25Editorial Expression of Concern: Tumour exosome integrins determine organotropic metastasis
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10977-8 Editorial Expression of Concern: Tumour exosome integrins determine organotropic metastasis
最高第 6 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时51分 - 26Operational Tropical Cyclone Forecasting with AI
Nature, Published online: 06 August 2026; doi:10.1038/s41586-026-10953-2 Operational Tropical Cyclone Forecasting with AI
最高第 1 名00:55 达到00:55 首次观测上榜当日结束时仍在榜累计约22小时56分 - 27Scientists up in arms about cuts to UK physics and astronomy
Nature, Published online: 06 August 2026; doi:10.1038/d41586-026-02460-1 Funding is being terminated for projects including a future CERN experiment and the iconic Lovell Telescope.
最高第 5 名01:27 达到01:27 首次观测上榜当日结束时仍在榜累计约22小时24分 - 28DCAF11-dependent molecular glue degrader activated by glutathionylation
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10873-1 M12 is a metabolically activated molecular glue that recruits diverse proteins to DCAF11 for ubiquitin-mediated degradation, revealing a glutathione-dependent mechanism that broadens targeted protein degradation across multiple substrates.
最高第 26 名00:00 达到当日首次采集时已在榜21:43 观测离榜累计约21小时43分 - 29Levitating sensor for magnetic fields could detect ultrafaint brain activity
Nature, Published online: 06 August 2026; doi:10.1038/d41586-026-02458-9 The device’s simple design could rival much more complex alternatives in biophysics research — and could even be used to search for dark matter.
最高第 4 名02:31 达到02:31 首次观测上榜当日结束时仍在榜累计约21小时20分 - 30Heatwaves have killed millions. Here’s how scientists tally lives lost
Nature, Published online: 06 August 2026; doi:10.1038/d41586-026-02430-7 Two very different methods are used to estimate the human toll of heatwaves such as those now hitting parts of Asia and Europe.
最高第 4 名19:35 达到05:43 首次观测上榜当日结束时仍在榜累计约18小时8分 - 31A cholinergic hub in the nucleus accumbens gates opioid-reward learning
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10887-9 Cell-type-specific opioid blockade in accumbal cholinergic interneurons abolishes morphine-reward learning without impairing analgesia and decouples morphine-evoked dopamine elevations from acetylcholine dips, suggesting pro-cholinergic strategies to limit early opioid reward acquisition.
最高第 27 名00:00 达到当日首次采集时已在榜05:43 观测离榜累计约5小时43分 - 32Vacuum birefringence and the polarized X-ray emission from a radio magnetar
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10859-z Polarization measurements of the magnetar 1E 1547.0−5408 provide strong evidence that vacuum birefringence shapes X-ray propagation, offering an important observational test of quantum electrodynamics in extreme magnetic fields.
最高第 28 名00:00 达到当日首次采集时已在榜02:31 观测离榜累计约2小时31分 - 33Briefing Chat: Is DNA repair the secret to a long life? Whales and mole rats offer tantalizing hints
Nature, Published online: 07 August 2026; doi:10.1038/d41586-026-02488-3 Nature staff discuss how animal studies are starting to uncover how DNA repair could prolong life, and how COVID-19 can reawaken dormant viruses.
最高第 1 名21:43 达到21:43 首次观测上榜当日结束时仍在榜累计约2小时8分 - 34An ancient mitochondrial program tunes translation to haem availability
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10885-x An evolutionarily conserved mitochondrial haem-sensing mechanism that predates the emergence of haemoglobin-based oxygen transport could have therapeutic value in iron deficiency disorders.
最高第 29 名00:00 达到当日首次采集时已在榜01:27 观测离榜累计约1小时27分 - 35<i>FNIP1</i> variants are associated with favourable metabolism in 1 million humans
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10864-2 The FNIP1 pathway has a role in human energy metabolism, and its inhibition is a potential therapeutic strategy in cardiometabolic disease.
最高第 30 名00:00 达到当日首次采集时已在榜00:55 观测离榜累计约55分钟



































