
Nature · 实时热榜
- 01Lead carboxylates passivation for meter-scale perovskite solar modules
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10994-7 Lead carboxylates passivation for meter-scale perovskite solar modules
最高第 1 名00:16 达到00:00 首次观测上榜当日结束时仍在榜累计约23小时43分 - 02The probiotic bacteria engineered to treat diabetes
Nature, Published online: 12 August 2026; doi:10.1038/d41586-026-02521-5 Genetically modified bacteria lower high blood-sugar in animal trials — plus, how to watch a solar eclipse safely.
最高第 4 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 03Numerous bow shocks in the outer Helix Nebula
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10724-z Shocks in the eastern outskirts of the Helix Nebula, detected in Hα emission with the MOTHRA telescope, provide evidence for the recycling of fragmented stellar ejecta into the surrounding gas.
最高第 21 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 04Shared principles of human and bacterial antiviral immunity
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10756-5 The Review describes shared ancient, conserved mechanisms between human antiviral immunity and bacterial anti-phage systems, outlining universal principles of pathogen sensing, signalling and effector function that reveal common rules governing host–virus interactions across life.
最高第 10 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 05Reply to: Pre-clinical data interpretation requires clinical context
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10773-4 Reply to: Pre-clinical data interpretation requires clinical context
最高第 2 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 06Pre-clinical data interpretation requires clinical context
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10774-3 Pre-clinical data interpretation requires clinical context
最高第 3 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 07Dataset artefacts can partially drive the measured decline in disruption
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10787-y Dataset artefacts can partially drive the measured decline in disruption
最高第 5 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 08Reply to: Dataset artefacts can partially drive the measured decline in disruption
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10788-x Reply to: Dataset artefacts can partially drive the measured decline in disruption
最高第 6 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 09Agentic profiles for effective AI governance
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10805-z A framework comprising four dimensions—autonomy, efficacy, goal complexity and generality—is proposed for characterizing AI agents, supporting the construction of agentic profiles for the effective governance of different AI agents.
最高第 7 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 10A gas-enshrouded and gas-reddened black hole at cosmic dawn
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10846-4 Observations of an unusual cosmic-dawn source illuminate how early supermassive black holes may have grown rapidly in a gas-enshrouded state; such enshrouded black holes may lie at the heart of the 'little red dots'.
最高第 14 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 11Species intraspecific variation drives tropical forest drought resistance
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10870-4 Substantial intraspecific variation, together with species turnover, drives coordinated shifts in drought resistance such as increased embolism resistance and wider stomatal safety margins in drier forests.
最高第 20 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 12Rb-driven transcription limits its tumour-suppressive effects in breast cancer
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10886-w CDK4/6 inhibition redirects Rb chromatin occupancy to activate oestrogen-responsive genes, counteracting its own ability to maintain therapeutic cell-cycle arrest.
最高第 12 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 13Cascading continental-scale floods across Europe in 1342–1343
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10888-8 Tracing cascading continental-scale medieval megafloods across Europe indicates that current flood management is unprepared for such sequences, highlighting the urgent need for proactive flood risk management strategies that account for unusual series of extreme flood events.
最高第 11 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 14Luminescent-reaction-enabled super-resolution imaging
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10889-7 A new chemistry-based super-resolution imaging framework is described, enabling 3D, laser-free, highly sensitive and ultralong-term imaging of live cells which overcomes the limitations in spatiotemporal resolution associated with reaction-based imaging methods.
最高第 16 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 15Degree-of-polarization modulation for high-dimensional optical computing
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10891-z By engineering the statistics of light at the micrometre scale using phase-only spatial light modulators, both the state and degree of polarization become spatially programmable, enabling direct encoding of information in a high-dimensional space.
最高第 17 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 16Neural basis of compositional control
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10896-8 Behaviour of human participants in a prey-pursuit task reflects dynamic blending of goal-specific control policies, with hippocampus estimating latent states, anterior cingulate cortex orchestrating policy switches and orbitofrontal cortex supplying value-based contextualization rather than driving continuous policy updating.
最高第 18 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 17Structural mechanism governing the directionality of bridge recombination
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10903-y Cryo-electron microscopy structures show how IS621 bridge recombinase mediates DNA excision, explaining its natural preference for insertion and informing the design of programmable bridge-editing technologies.
最高第 19 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 18Towards an equitable future of global photovoltaic waste recycling
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10905-w Global photovoltaic waste will reach 297–402 million tonnes by 2060, and regionally adapted recycling strategies and international cooperation will be needed to provide equitable and scalable PV waste circularity.
最高第 15 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 19Procognitive restoration of PV neuron plasticity in neurodevelopmental disorders
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10907-8 Expression of Meis2 in hippocampal parvalbumin-expressing interneurons in an adult mouse model of neurodevelopmental disorders rescues experience-dependent plasticity, improves memory and network function and suppresses seizures.
最高第 13 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 20Glucose-responsive probiotics for glycaemic modulation in mice and monkeys
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10909-6 Engineered probiotics equipped with a synthetic glucose-responsive circuit transiently colonize the gut and secrete therapeutic factors when glucose levels increase, enabling safe, oral, sense-and-respond control of diabetes in mouse and primate models.
最高第 8 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 21Temporal uncoupling of radial glia lineage progression in cortical organoids
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10916-7 RGP lineage tracing in stem-cell-derived organoids shows highly plastic proliferation and reduced clonal neuronal diversity, indicating that missing non-cell-autonomous niche cues are essential for faithful temporal control of cortical lineage progression.
最高第 9 名00:16 达到00:16 首次观测上榜当日结束时仍在榜累计约23小时27分 - 22Evidence for the first globular cluster stellar stream beyond the Milky Way
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10878-w Deep Hubble Space Telescope imaging of the ultra-diffuse galaxy UGC 9050-Dw1 reveals an extragalactic globular cluster stream, with analysis and modelling probing the rich dark matter content of the host galaxy.
最高第 23 名00:16 达到00:16 首次观测上榜23:28 观测离榜累计约23小时11分 - 23Maternal influences on infant gut microbiome and health
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10922-9 The maternal gut microbiome is a predictor of infant eczema.
最高第 22 名00:16 达到00:16 首次观测上榜23:28 观测离榜累计约23小时11分 - 24Superconducting 2D cuprate with a single CuO<sub>2</sub> plane
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10857-1 A high-quality, pristine monolayer cuprate superconductor with a single CuO2 plane is fabricated and used to identify two quantum critical phenomena emerging between the Mott insulating phase and the superconducting phase.
最高第 25 名00:16 达到00:16 首次观测上榜22:24 观测离榜累计约22小时8分 - 25Heterogeneous climatic controls on tropical-forest biomass
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10880-2 An analysis of the relationships between aboveground biomass and various climatic factors in three major regions of tropical forest shows that understanding the complex interactions between climate, topography and soils is crucial to predict how climate change will affect carbon storage capacity.
最高第 24 名00:16 达到00:16 首次观测上榜22:24 观测离榜累计约22小时8分 - 26In vivo genome-wide CRISPR screens of human T cells in solid tumours
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10906-9 An in vivo model that is able to recover human T cells from solid tumours can identify targets to help improve CAR T cell antitumour activity.
最高第 26 名00:16 达到00:16 首次观测上榜21:20 观测离榜累计约21小时4分 - 27Biomarkers of nivolumab benefit in resectable non-small cell lung cancer
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10925-6 Potential predictive biomarkers of perioperative nivolumab therapy benefit in non-small cell lung cancer are identified from evaluable participants in the CheckMate 77T trial.
最高第 27 名00:16 达到00:16 首次观测上榜20:32 观测离榜累计约20小时16分 - 28Rattlesnakes’ own antivenom could protect humans too
Nature, Published online: 12 August 2026; doi:10.1038/d41586-026-02461-0 A mixture of proteins in snake blood can prevent the death of mice injected with an otherwise lethal dose of venom.
最高第 5 名03:28 达到03:28 首次观测上榜当日结束时仍在榜累计约20小时15分 - 29Giant balloon gives rise to new view of the Milky Way’s centre
Nature, Published online: 12 August 2026; doi:10.1038/d41586-026-02463-y Airborne camera gathers data about the high-energy particles emanating from the core of our Galaxy.
最高第 4 名03:28 达到03:28 首次观测上榜当日结束时仍在榜累计约20小时15分 - 30How the human brain can pursue two goals at the same time
Nature, Published online: 12 August 2026; doi:10.1038/d41586-026-02395-7 In the natural world, an animal can blend strategies so it can advance towards several goals at the same time. An engineering approach called control theory was used to infer people’s goals while they played a simple video game, and showed how three brain regions work together to implement goal blending.
最高第 28 名00:16 达到00:16 首次观测上榜17:20 观测离榜累计约17小时4分 - 31Author Correction: Cretaceous bird from Brazil informs the evolution of the avian skull and brain
Nature, Published online: 13 August 2026; doi:10.1038/s41586-026-10960-3 Author Correction: Cretaceous bird from Brazil informs the evolution of the avian skull and brain
最高第 1 名17:20 达到17:20 首次观测上榜当日结束时仍在榜累计约6小时23分 - 32Human brain stimulation engages different gene programs in different cell types
Nature, Published online: 12 August 2026; doi:10.1038/d41586-026-02473-w Electrical stimulation of the human brain is a promising strategy for slowing cognitive decline. The discovery of cell-type-specific gene programs that are induced in tandem with the activity of networks of neurons in the temporal cortex when it is stimulated could inform the development of therapeutic approaches using stimulation.
最高第 29 名00:16 达到00:16 首次观测上榜03:28 观测离榜累计约3小时12分 - 33Ultrafast temporal engineering of optical properties using terahertz light
Nature, Published online: 12 August 2026; doi:10.1038/d41586-026-02478-5 A photonic time crystal is an optical system of which properties such as its refractive index are modulated strongly and rapidly over time. One has now been obtained all-optically by delivering an intense terahertz light wave onto a material with a specialized microstructure that hosts collective waves of electrons known as plasmons.
最高第 30 名00:16 达到00:16 首次观测上榜03:28 观测离榜累计约3小时12分 - 34How to make your science business succeed when you’re a female founder
Nature, Published online: 13 August 2026; doi:10.1038/d41586-026-01904-y Sexist assumptions and a male-dominated culture can make it harder for women to attract investment for the companies they set up.
最高第 2 名20:32 达到20:32 首次观测上榜当日结束时仍在榜累计约3小时11分 - 35AI isn’t ready to research itself
Nature, Published online: 13 August 2026; doi:10.1038/d41586-026-02494-5 An agentic system successfully developed concepts from two computer-science papers — but the original authors were not impressed.
最高第 3 名21:20 达到21:20 首次观测上榜当日结束时仍在榜累计约2小时23分 - 36Can Anthropic’s invisible watermarks curb ‘AI slop’? Researchers remain sceptical
Nature, Published online: 13 August 2026; doi:10.1038/d41586-026-02503-7 New Claude models will watermark text and tag images as AI-generated, as Anthropic responds to EU AI regulations.
最高第 3 名22:24 达到22:24 首次观测上榜当日结束时仍在榜累计约1小时19分 - 37Why China should reassess how it rewards young scientists
Nature, Published online: 13 August 2026; doi:10.1038/d41586-026-02525-1 Talent schemes helped to propel China to the forefront of global science. But the system places undue emphasis on prestigious titles as a means to secure career prospects, putting pressure on young researchers.
最高第 5 名22:24 达到22:24 首次观测上榜当日结束时仍在榜累计约1小时19分 - 38Establishment and characterization of multiple myeloma cell lines from a single patient’s disease course immortalizes clonal heterogeneity
Nature, Published online: 12 August 2026; doi:10.1038/s41408-026-01597-6 Establishment and characterization of multiple myeloma cell lines from a single patient’s disease course immortalizes clonal heterogeneity
最高第 18 名00:00 达到当日首次采集时已在榜00:16 观测离榜累计约17分钟 - 39Author Correction: Effective in vivo RNA base editing via engineered cytidine deaminase APOBECs fused with PUF proteins
Nature, Published online: 12 August 2026; doi:10.1038/s41467-026-76669-z Author Correction: Effective in vivo RNA base editing via engineered cytidine deaminase APOBECs fused with PUF proteins
最高第 9 名00:00 达到当日首次采集时已在榜00:16 观测离榜累计约17分钟 - 40Human in vitro skeletal muscle models recapitulate age-related atrophy and contractile decline induced by aged serum
Nature, Published online: 12 August 2026; doi:10.1038/s41514-026-00472-9 Human in vitro skeletal muscle models recapitulate age-related atrophy and contractile decline induced by aged serum
最高第 24 名00:00 达到当日首次采集时已在榜00:16 观测离榜累计约17分钟 - 41Field measurements of dune erosion and hydrodynamics during the Hybrid Dune experiment
Nature, Published online: 12 August 2026; doi:10.1038/s41597-026-07985-8 Field measurements of dune erosion and hydrodynamics during the Hybrid Dune experiment
最高第 26 名00:00 达到当日首次采集时已在榜00:16 观测离榜累计约17分钟 - 42Dataset of GenAI-Assisted Information Problem Solving in Education
Nature, Published online: 12 August 2026; doi:10.1038/s41597-026-08054-w Dataset of GenAI-Assisted Information Problem Solving in Education
最高第 25 名00:00 达到当日首次采集时已在榜00:16 观测离榜累计约17分钟 - 43The chromosome-level genome of the synchronously flashing firefly <italic>Pygoluciola qingyu</italic> (Coleoptera: Lampyridae)
Nature, Published online: 12 August 2026; doi:10.1038/s41597-026-08078-2 The chromosome-level genome of the synchronously flashing firefly Pygoluciola qingyu (Coleoptera: Lampyridae)
最高第 27 名00:00 达到当日首次采集时已在榜00:16 观测离榜累计约17分钟 - 44A high-resolution RNA interaction atlas of <italic>Arabidopsis</italic> TUDOR STAPHYLOCOCCAL NUCLEASE1 by <italic>in vivo</italic> iCLIP
Nature, Published online: 12 August 2026; doi:10.1038/s41597-026-08094-2 A high-resolution RNA interaction atlas of Arabidopsis TUDOR STAPHYLOCOCCAL NUCLEASE1 by in vivo iCLIP
最高第 22 名00:00 达到当日首次采集时已在榜00:16 观测离榜累计约17分钟 - 45Model-free multiparametric analysis of SHG images reveals collagen signatures in breast cancer
Nature, Published online: 12 August 2026; doi:10.1038/s41598-026-62801-y Model-free multiparametric analysis of SHG images reveals collagen signatures in breast cancer
最高第 1 名00:00 达到当日首次采集时已在榜00:16 观测离榜累计约17分钟 - 46Correction: A five-dimensional classical framework for gravitational and quantum phenomena
Nature, Published online: 12 August 2026; doi:10.1038/s41598-026-63846-9 Correction: A five-dimensional classical framework for gravitational and quantum phenomena
最高第 8 名00:00 达到当日首次采集时已在榜00:16 观测离榜累计约17分钟 - 47Training neural networks on mechanistic simulations improves scientific inference
Nature, Published online: 12 August 2026; doi:10.1038/s41598-026-64106-6 Training neural networks on mechanistic simulations improves scientific inference
最高第 11 名00:00 达到当日首次采集时已在榜00:16 观测离榜累计约17分钟 - 48AlzheiNN: a convolutional neural network-based model for Alzheimer’s disease classification
Nature, Published online: 12 August 2026; doi:10.1038/s41598-026-64954-2 AlzheiNN: a convolutional neural network-based model for Alzheimer’s disease classification
最高第 3 名00:00 达到当日首次采集时已在榜00:16 观测离榜累计约17分钟 - 49Optimizing real-time rescheduling mechanism for flexible manufacturing systems considering equipment fault disturbances using HGNN-PPO cooperative policy learning algorithm
Nature, Published online: 12 August 2026; doi:10.1038/s41598-026-65082-7 Optimizing real-time rescheduling mechanism for flexible manufacturing systems considering equipment fault disturbances using HGNN-PPO cooperative policy learning algorithm
最高第 16 名00:00 达到当日首次采集时已在榜00:16 观测离榜累计约17分钟 - 50Increased urinary podocyte mRNA loss in term small for gestational age infants
Nature, Published online: 12 August 2026; doi:10.1038/s41598-026-65629-8 Increased urinary podocyte mRNA loss in term small for gestational age infants
最高第 15 名00:00 达到当日首次采集时已在榜00:16 观测离榜累计约17分钟



































