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Nature, Published online: 19 August 2026; doi:10.1038/d41586-026-02037-y Scientists share help and advice on how they got their research discussions flowing.

Nature, Published online: 19 August 2026; doi:10.1038/d41586-026-02516-2 Many researchers are unaware of an upcoming law that will require them to register with a regulatory body, as is the case for engineers and health-care professionals.

Nature, Published online: 19 August 2026; doi:10.1038/d41586-026-02537-x Viruses that infect bacteria must either evade or counter the defence systems of their host. The viral kinase enzyme T7K has been found to phosphorylate nearly all bacterial proteins, but its specificity for DNA-binding proteins enables it to disable defence systems that target nucleic acids.

Nature, Published online: 19 August 2026; doi:10.1038/d41586-026-02607-0 Star orbiting close to Sagittarius A* could reveal its spin — plus, how exoskeletons might change the way humans move.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10687-1 The Review examines rapid LLM adoption in clinical care, outlining emerging security and safety risks across development stages, key protective layers, clinically relevant threats and current mitigation responsibilities in a single integrated framework.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10776-1 Reply to: Artefacts in single-cell mtDNA analyses misinform phylogenies

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10777-0 Artefacts in single-cell mtDNA analyses misinform phylogenies

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10877-x Human brain organoids were developed for over five years in culture to demonstrate that brain cells can continue to mature and record the passage of time, following human-specific endogenous programs, even outside the context of the organism.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10892-y AP-7-168, an optimized derivative of a β-arrestin-biased negative allosteric modulator of the β2-adrenergic receptor (β2AR), functions as a molecular glue to stabilize β2AR homodimerization.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10894-w The discovery of the fast-orbiting star S301 near Sagittarius A* offers a promising new probe of the central black hole spin of the Milky Way through relativistic orbit measurements.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10900-1 Mice spontaneously form leader and follower roles during cooperation, and the medial prefrontal cortex encodes these role dynamics and an egocentric social value map of the partner’s position.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10904-x Measurements on an array of optically trapped neutral atoms at a quantum phase transition provide a direct observation of the universal excitation spectrum predicted by conformal field theory.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10910-z The psychedelic psilocybin reorganizes brain activity into structured, context-aligned patterns that integrate internal and external processing, providing a neural basis for the felt continuity between self and world, elucidating how the psychedelic state translates into psychological change.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10912-x Recent Antarctic ice mass gain was linked to a recurrent atmospheric teleconnection, but this recurs about once per decade in observations and historical simulations so does not yet reflect a global-warming-driven moistening of Antarctica.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10914-9 Double-slit interferometry at the atomic scale is demonstrated using scanning transmission electron microscopy to provide evidence of interference fringes generated with a focused electron beam encountering two silicon atomic columns separated by 1.36 Å.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10917-6 HydroGym offers over 60 standardized reinforcement-learning flow-control environments and demonstrates zero-shot transfer to a 3D wing, cutting local skin friction by 38% and exploration costs by four orders of magnitude.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10924-7 Newly developed methods enable construction of Icelandic haplotypes and mapping of population-scale short reads to a pangenome by reducing reference bias and improving discovery in low-mappability regions, revealing many novel variants, including pathogenic alleles.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10926-5 The Norwegian Mother, Father and Child Cohort Study demonstrates how family-based genomic data can disentangle direct genetic effects from confounding, improving studies of health and human development.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10928-3 Whole-brain activity mapping, targeted cell manipulations and electrophysiology in mice identify wake-activated neuronal populations that are crucial for sleep drive and can persistently reduce daily sleep amount.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10933-6 A one-pot skeletal-editing reaction replaces isoxazole oxygen with carbon to form challenging pyrroles, enabled by an N-propargylic enaminone intermediate and a computational model predicting reaction outcomes.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10934-5 The T7 bacteriophage deactivates bacterial defence systems through T7K phosphorylation of nearly all host and phage proteins during infection.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10935-4 By combining a meta-analysis of CO2 enrichment experiments with three decades of southern African savanna observations, an increase in biomass production by C4 grasses under rising CO2 levels in water-limited environments is revealed.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10938-1 A 2,000-year Peruvian ice core record of atmospheric CH4 concentrations contains the first historical global CH4 record from the low latitudes, and implementation of a four-box model indicates higher equatorial CH4 strength than previous estimates from polar-only records.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10951-4 Functional lymphoid structures within the skull bone marrow enable central nervous system immunosurveillance and shape immune responses to brain disease.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-11037-x Evidence for vacuum-enhanced superconductivity in NbSe 2

Nature, Published online: 19 August 2026; doi:10.1038/d41586-026-02554-w Female treefrogs select less carefully when hearing a chorus of males.

Nature, Published online: 19 August 2026; doi:10.1038/d41586-026-02587-1 Research on people 110 years and older reveals an immune system that continues to adapt.

Nature, Published online: 19 August 2026; doi:10.1038/d41586-026-02377-9 Rather than just scrambling neural activity, the psychedelic substance psilocybin also reorganizes brain dynamics so as to align with a person’s context and experiences.

Nature, Published online: 19 August 2026; doi:10.1038/d41586-026-02528-y Massive genomic newborn-screening studies are under way all over the globe. But questions about scalability, feasibility and net benefit remain.

Nature, Published online: 20 August 2026; doi:10.1038/d41586-026-02586-2 They release compounds that contribute to ozone emissions, and rising temperatures could exacerbate the problem.

Nature, Published online: 19 August 2026; doi:10.1038/d41586-026-02610-5 His calculations explain the efficiency of batteries and solar cells.

Nature, Published online: 20 August 2026; doi:10.1038/d41586-026-02549-7 The approach could speed up investment decisions, but researchers say it has flaws.

Nature, Published online: 20 August 2026; doi:10.1038/d41586-026-02553-x Adding albumin to popular antibody-based medicines helps to block their passage through the placenta.

Nature, Published online: 20 August 2026; doi:10.1038/d41586-026-02612-3 Promising trial results suggest cancer vaccines work and could be used to target other tumours.

Nature, Published online: 19 August 2026; doi:10.1038/d41586-026-02495-4 An autonomous AI agent can write and execute quantum computing code, but it sometimes needs a human touch.

Nature, Published online: 18 August 2026; doi:10.1038/d41586-026-01932-8 These informal meetings can help you to explore new career opportunities, but there is a knack to getting them right.

Nature, Published online: 18 August 2026; doi:10.1038/d41586-026-02381-z Researchers grapple with the causes of evolution, and a sea voyage is blighted by storms, in our weekly dip into Nature’s archive.

Nature, Published online: 19 August 2026; doi:10.1038/d41586-026-02410-x Called to account.

Nature, Published online: 18 August 2026; doi:10.1038/d41586-026-02466-9 A topological description of ‘knittability’ can be used to design yarn patterns that are resistant to unravelling.

Nature, Published online: 18 August 2026; doi:10.1038/d41586-026-02524-2 It is 20 years since induced pluripotent stem cells shook biomedicine. Public trust must be retained now that clinical trials are well under way.

Nature, Published online: 17 August 2026; doi:10.1038/d41586-026-02526-0 Letting powerful academics off the hook and punishing the people they bullied sends the message that abuse is acceptable in academia.

Nature, Published online: 18 August 2026; doi:10.1038/d41586-026-02527-z Robotic supports were once designed for clinical use, but researchers are now developing cheaper, smaller devices aimed at everyone — from people with ageing knees to 20-somethings seeking to climb mountains.

Nature, Published online: 17 August 2026; doi:10.1038/d41586-026-02529-x History shows that breakthroughs are often sparked by innovative instruments, and AI’s ability to help design them might be its most important scientific contribution.

Nature, Published online: 17 August 2026; doi:10.1038/d41586-026-02530-4 Earth’s four-billion-year-long conversation with its resident life forms has shaped our world, and holds lessons for our future.

Nature, Published online: 18 August 2026; doi:10.1038/d41586-026-02531-3 Building on the region’s oil infrastructure, investment funds and shipping corridors, Gulf nations can thrive in the clean-energy economy.

Nature, Published online: 17 August 2026; doi:10.1038/d41586-026-02532-2 As climate change ramps up, scientists must urgently understand how night-time heat makes it harder for our bodies to rest and recover.

Nature, Published online: 18 August 2026; doi:10.1038/d41586-026-02535-z As 3D printers become cheaper and easier to work with, researchers are finding new ways to incorporate the technology in their studies.

Nature, Published online: 17 August 2026; doi:10.1038/d41586-026-02552-y The drug, called Orzeyful, takes aim at the root cause of the sleep disorder rather than at its symptoms.

Nature, Published online: 18 August 2026; doi:10.1038/d41586-026-02575-5 Treat biological databases as infrastructure, not projects

Nature, Published online: 18 August 2026; doi:10.1038/d41586-026-02576-4 Asia’s longevity gains must be translated into better health