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PubMed · 实时热榜

HISTORY2026年8月30日70 不同热搜
08/0309/01 有历史数据
DAILY UNIQUE TOPICS70 个热搜
  1. 01
    Intraosseous calvarial haematoma mimicking a skull tumour in a child with Noonan syndrome: a case report.

    趋势排名:2 · 期刊:Journal of surgical case reports · 类型:Journal Article · 语言:eng · PMID:42639270 · DOI:10.1093/jscr/rjag743 · PMC:PMC13502394

    最高第 100:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  2. 02
    Neuroimaging Abnormalities and Genotype-Phenotype Correlations in Noonan Syndrome: A Multicenter Cohort Study.

    趋势排名:1 · 期刊:The Journal of clinical endocrinology and metabolism · 类型:Journal Article · 语言:eng · PMID:42657773 · DOI:10.1210/clinem/dgag352

    最高第 122:24 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  3. 03
    Sex-specific aging clocks from a large-scale human phenome reveal distinct aging transitions and circulating signatures.

    趋势排名:6 · 期刊:Nature aging · 类型:Journal Article · 语言:eng · PMID:42642518 · DOI:10.1038/s43587-026-01180-5

    最高第 200:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  4. 04
    Effects of perceived treatment on quality of life and medical outcomes in a double-blind placebo surgery trial.

    趋势排名:3 · 期刊:Archives of general psychiatry · 类型:Randomized Controlled Trial · 语言:eng · PMID:15066900 · DOI:10.1001/archpsyc.61.4.412

    最高第 322:24 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  5. 05
    Objective monitoring tools for improved management of childhood asthma.

    趋势排名:8 · 期刊:Respiratory research · 类型:Review · 语言:eng · PMID:38702779 · DOI:10.1186/s12931-024-02817-y · PMC:PMC11069259

    最高第 300:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  6. 06
    Beyond Bone Health: Exploring the "Heart-Brain-Bone" Axis Modulated by Lipid-Soluble Nutrients (Omega-3, Vitamin D3, and Vitamin K2).

    趋势排名:3 · 期刊:Nutrients · 类型:Review · 语言:eng · PMID:42654291 · DOI:10.3390/nu18162711 · PMC:PMC13516505

    最高第 304:32 达到01:52 首次观测上榜14:56 观测离榜上榜 14 次(重入 13 次)累计约6小时8分
  7. 07
    Sex and Gender Differences in Physical Activity, Sedentary Behavior, and Sleep During Traumatic Brain Injury Recovery: A Narrative Review.

    趋势排名:4 · 期刊:European journal of sport science · 类型:Review · 语言:eng · PMID:42658054 · DOI:10.1002/ejsc.70248 · PMC:PMC13520797

    最高第 422:24 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  8. 08
    Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart disease in a Hong Kong Chinese population.

    趋势排名:16 · 期刊:Diabetes research and clinical practice · 类型:Journal Article · 语言:eng · PMID:22515931 · DOI:10.1016/j.diabres.2012.03.012

    最高第 501:20 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  9. 09
    Prehospital epinephrine as a bridge to survival in traumatic cardiac arrest: A nationwide propensity score-matched analysis.

    趋势排名:9 · 期刊:The American journal of emergency medicine · 类型:Journal Article · 语言:eng · PMID:42372567 · DOI:10.1016/j.ajem.2026.06.039

    最高第 500:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  10. 10
    2026 ESC Guidelines for the management of heart failure.

    趋势排名:5 · 期刊:European heart journal · 类型:Journal Article · 语言:eng · PMID:42661420 · DOI:10.1093/eurheartj/ehag100

    最高第 522:24 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  11. 11
    2026 Guideline for Adult Stroke Rehabilitation and Recovery: A Guideline From the American Heart Association and American Stroke Association.

    趋势排名:7 · 期刊:Stroke · 类型:Review · 语言:eng · PMID:42657476 · DOI:10.1161/STR.0000000000000536

    最高第 619:12 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  12. 12
    Discovery of 4H-Chromen-4-one Derivatives as a New Class of Selective Rho Kinase (ROCK) Inhibitors, which Showed Potent Activity in ex Vivo Diabetic Retinopathy Models.

    趋势排名:10 · 期刊:Journal of medicinal chemistry · 类型:Journal Article · 语言:eng · PMID:31693351 · DOI:10.1021/acs.jmedchem.9b01143

    最高第 800:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  13. 13
    Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2).

    趋势排名:17 · 期刊:Bioorganic & medicinal chemistry · 类型:Journal Article · 语言:eng · PMID:26762835 · DOI:10.1016/j.bmc.2015.11.045 · PMC:PMC5947326

    最高第 900:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  14. 14
    Novel quinazoline derivatives bearing various 6-benzamide moieties as highly selective and potent EGFR inhibitors.

    趋势排名:11 · 期刊:Bioorganic & medicinal chemistry · 类型:Journal Article · 语言:eng · PMID:29523467 · DOI:10.1016/j.bmc.2018.02.022

    最高第 901:20 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  15. 15
    Effect of Workplace Violence on Turnover Intention: The Mediating Roles of Job Control, Psychological Demands, and Social Support.

    趋势排名:31 · 期刊:Inquiry : a journal of medical care organization, provision and financing · 类型:Journal Article · 语言:eng · PMID:33334214 · DOI:10.1177/0046958020969313 · PMC:PMC7750754

    最高第 1100:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  16. 16
    Characteristics of Vaginal Microbiome in Reproductive-Age Females with HPV Infection in Xinjiang, China.

    趋势排名:14 · 期刊:Evidence-based complementary and alternative medicine : eCAM · 类型:Journal Article · 语言:eng · PMID:36387363 · DOI:10.1155/2022/7332628 · PMC:PMC9643059

    最高第 1207:12 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  17. 17
    On-demand transarterial chemoembolisation combined with atezolizumab and bevacizumab in patients with untreated hepatocellular carcinoma (TALENTACE): a multicentre, randomised, open-label, phase 3 trial.

    趋势排名:33 · 期刊:The lancet. Gastroenterology & hepatology · 类型:Journal Article · 语言:eng · PMID:42641632 · DOI:10.1016/S2468-1253(26)00212-8

    最高第 1200:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  18. 18
    SGLT2 inhibitors activate pantothenate kinase in the human heart.

    趋势排名:12 · 期刊:Science (New York, N.Y.) · 类型:Journal Article · 语言:eng · PMID:42658934 · DOI:10.1126/science.aeh4856

    最高第 1222:24 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  19. 19
    Durvalumab and tremelimumab, with or without lenvatinib, combined with transarterial chemoembolisation in participants with embolisation-eligible hepatocellular carcinoma (EMERALD-3): a global, randomised, open-label, sponsor-blinded, phase 3 study.

    趋势排名:35 · 期刊:The Lancet. Oncology · 类型:Randomized Controlled Trial · 语言:eng · PMID:42636832 · DOI:10.1016/S1470-2045(26)00278-0

    最高第 1300:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  20. 20
    A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease.

    趋势排名:13 · 期刊:Science (New York, N.Y.) · 类型:Journal Article · 语言:eng · PMID:42658927 · DOI:10.1126/science.aeh7112

    最高第 1322:24 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  21. 21
    Postural Orthostatic Tachycardia Syndrome (POTS): A Review.

    趋势排名:37 · 期刊:JAMA · 类型:Journal Article · 语言:eng · PMID:42635998 · DOI:10.1001/jama.2026.14809

    最高第 1500:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  22. 22
    Autism mutations rewire protein interaction networks to drive neurodevelopmental pathology.

    趋势排名:15 · 期刊:Science (New York, N.Y.) · 类型:Journal Article · 语言:eng · PMID:42658940 · DOI:10.1126/science.ady4523

    最高第 1510:08 达到当日首次采集时已在榜当日结束时仍在榜上榜 2 次(重入 1 次)累计约23小时13分
  23. 23
    Toward unified and comprehensive automated electroencephalogram interpretation: a multicentre development and validation of an electroencephalogram foundation model.

    趋势排名:40 · 期刊:The Lancet. Digital health · 类型:Journal Article · 语言:eng · PMID:42642264 · DOI:10.1016/j.landig.2026.101039

    最高第 1700:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  24. 24
    Nonviral delivery of chemically modified tRNA rescues nonsense mutations in cystic fibrosis.

    趋势排名:18 · 期刊:Science (New York, N.Y.) · 类型:Journal Article · 语言:eng · PMID:42658930 · DOI:10.1126/science.aeb0054

    最高第 1719:12 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  25. 25
    A geroprotective probiotic and its functional metabolite counteract inflammaging to extend healthspan.

    趋势排名:41 · 期刊:Nature aging · 类型:Journal Article · 语言:eng · PMID:42642521 · DOI:10.1038/s43587-026-01181-4

    最高第 1800:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  26. 26
    Generational IQ: Quasilongitudinal insights from the Wechsler Adult Intelligence Scale, Fifth Edition.

    趋势排名:19 · 期刊:Developmental psychology · 类型:Journal Article · 语言:eng · PMID:42329721 · DOI:10.1037/dev0002226

    最高第 1904:16 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  27. 27
    NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.

    趋势排名:22 · 期刊:ChemMedChem · 类型:Journal Article · 语言:eng · PMID:29928781 · DOI:10.1002/cmdc.201800398

    最高第 2000:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  28. 28
    SARS-CoV-2 disrupts the integrity of a human blood-brain barrier model in the absence of infection.

    趋势排名:21 · 期刊:Journal of neurovirology · 类型:Journal Article · 语言:eng · PMID:42645657 · DOI:10.1007/s13365-026-01337-3 · PMC:PMC13518450

    最高第 2018:56 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  29. 29
    Sex differences in blood pressure variability during critical illness: a retrospective cohort study.

    趋势排名:20 · 期刊:Open heart · 类型:Journal Article · 语言:eng · PMID:42665291 · DOI:10.1136/openhrt-2025-003701

    最高第 2022:24 达到16:16 首次观测上榜当日结束时仍在榜累计约7小时28分
  30. 30
    Randomized, double-blind, placebo-controlled trial of saw palmetto in men with lower urinary tract symptoms.

    趋势排名:25 · 期刊:Urology · 类型:Randomized Controlled Trial · 语言:eng · PMID:11744467 · DOI:10.1016/s0090-4295(01)01442-x

    最高第 2318:56 达到01:20 首次观测上榜当日结束时仍在榜累计约22小时24分
  31. 31
    A binding-to-release strategy for targeted anticancer drug delivery.

    趋势排名:24 · 期刊:Nature · 类型:Journal Article · 语言:eng · PMID:42649302 · DOI:10.1038/s41586-026-10971-0

    最高第 2319:12 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  32. 32
    Sporotrichosis associated with sphagnum moss exposure.

    趋势排名:23 · 期刊:Archives of pathology & laboratory medicine · 类型:Journal Article · 语言:eng · PMID:6450578

    最高第 2322:24 达到16:16 首次观测上榜当日结束时仍在榜累计约7小时28分
  33. 33
    Prevalence of chronic traumatic encephalopathy at death in National Football League players: retrospective population based cohort study, 2008-21.

    趋势排名:49 · 期刊:BMJ (Clinical research ed.) · 类型:Journal Article · 语言:eng · PMID:42642105 · DOI:10.1136/bmj-2026-100418

    最高第 2400:00 达到当日首次采集时已在榜19:12 观测离榜累计约19小时13分
  34. 34
    Glucagon-Like Peptide 1 Receptor Agonists, Mortality, and Cardiovascular Outcomes in Serious Mental Illness.

    趋势排名:26 · 期刊:JAMA psychiatry · 类型:Journal Article · 语言:eng · PMID:42647034 · DOI:10.1001/jamapsychiatry.2026.2574

    最高第 2418:56 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  35. 35
    Oligodendrocyte dysfunction in human age-related cognitive decline.

    趋势排名:35 · 期刊:Nature medicine · 类型:Journal Article · 语言:eng · PMID:42642661 · DOI:10.1038/s41591-026-04608-y

    最高第 2500:00 达到当日首次采集时已在榜22:24 观测离榜累计约22小时25分
  36. 36
    Heritable transgenic schistosomes as a living platform for SARS-CoV-2 neutralizing antibody secretion.

    趋势排名:25 · 期刊:Nature communications · 类型:Journal Article · 语言:eng · PMID:42649193 · DOI:10.1038/s41467-026-76465-9 · PMC:PMC13518888

    最高第 2520:32 达到20:32 首次观测上榜23:44 观测离榜上榜 3 次(重入 2 次)累计约2小时8分
  37. 37
    ROCK inhibitors 3: Design, synthesis and structure-activity relationships of 7-azaindole-based Rho kinase (ROCK) inhibitors.

    趋势排名:29 · 期刊:Bioorganic & medicinal chemistry letters · 类型:Journal Article · 语言:eng · PMID:30082069 · DOI:10.1016/j.bmcl.2018.06.040

    最高第 2618:56 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  38. 38
    Association of Easier Biologic Access with Remission and Other Clinical Outcomes in Severe Asthma: A Global Real-World Study.

    趋势排名:26 · 期刊:Journal of asthma and allergy · 类型:Journal Article · 语言:eng · PMID:42638984 · DOI:10.2147/JAA.S597657 · PMC:PMC13501352

    最高第 2600:00 达到当日首次采集时已在榜01:20 观测离榜累计约1小时21分
  39. 39
    Case Report: A rare case of multi-vessel coronary artery-coronary sinus fistula combined with multiple coronary aneurysms initially presenting with frequent premature ventricular complexes.

    趋势排名:36 · 期刊:Frontiers in cardiovascular medicine · 类型:Journal Article · 语言:eng · PMID:42643173 · DOI:10.3389/fcvm.2026.1920885 · PMC:PMC13503148

    最高第 2700:00 达到当日首次采集时已在榜22:24 观测离榜累计约22小时25分
  40. 40
    Aberrant excitatory neuronal ERBB4 promotes Alzheimer's disease pathology.

    趋势排名:30 · 期刊:Nature · 类型:Journal Article · 语言:eng · PMID:42649291 · DOI:10.1038/s41586-026-10964-z

    最高第 2719:12 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  41. 41
    American Society for Gastrointestinal Endoscopy guideline on the role of endoscopy in acute lower gastrointestinal bleeding.

    趋势排名:27 · 期刊:Gastrointestinal endoscopy · 类型:Journal Article · 语言:eng · PMID:42667281 · DOI:10.1016/j.gie.2026.06.046

    最高第 2722:41 达到19:12 首次观测上榜当日结束时仍在榜累计约4小时32分
  42. 42
    ROCK inhibitors 2. Improving potency, selectivity and solubility through the application of rationally designed solubilizing groups.

    趋势排名:34 · 期刊:Bioorganic & medicinal chemistry letters · 类型:Journal Article · 语言:eng · PMID:29945794 · DOI:10.1016/j.bmcl.2018.06.043

    最高第 2818:56 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  43. 43
    2026 ESC Guidelines for the management of cardiovascular disease and chronic kidney disease, in collaboration with the European Renal Association (ERA).

    趋势排名:28 · 期刊:European heart journal · 类型:Journal Article · 语言:eng · PMID:42661426 · DOI:10.1093/eurheartj/ehag098

    最高第 2822:41 达到16:16 首次观测上榜当日结束时仍在榜累计约7小时28分
  44. 44
    Changes in vascular structure and function in primary hyperparathyroidism: a systematic review and meta-analysis.

    趋势排名:38 · 期刊:Frontiers in endocrinology · 类型:Systematic Review · 语言:eng · PMID:42643311 · DOI:10.3389/fendo.2026.1896180 · PMC:PMC13503531

    最高第 3100:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分
  45. 45
    Ivonescimab plus chemotherapy versus placebo plus chemotherapy in patients with advanced EGFR-mutated non-small-cell lung cancer after disease progression on EGFR tyrosine kinase inhibitor therapy (HARMONi): a multicentre, randomised, double-blind, phase 3 trial.

    趋势排名:37 · 期刊:The Lancet. Oncology · 类型:Randomized Controlled Trial · 语言:eng · PMID:42636833 · DOI:10.1016/S1470-2045(26)00282-2

    最高第 3200:00 达到当日首次采集时已在榜16:16 观测离榜累计约16小时17分
  46. 46
    CD19 CAR T cell therapy for treatment-refractory seropositive rheumatoid arthritis: a phase 1 trial.

    趋势排名:32 · 期刊:Nature medicine · 类型:Journal Article · 语言:eng · PMID:42661098 · DOI:10.1038/s41591-026-04603-3

    最高第 3222:41 达到19:12 首次观测上榜当日结束时仍在榜累计约4小时32分
  47. 47
    Childhood trauma and suicide ideation and attempts: Examining the mediating role of psychosocial, personality, lifestyle and biological factors.

    趋势排名:40 · 期刊:Journal of affective disorders · 类型:Journal Article · 语言:eng · PMID:42637149 · DOI:10.1016/j.jad.2026.122414

    最高第 3300:00 达到当日首次采集时已在榜16:16 观测离榜累计约16小时17分
  48. 48
    Electronic Health Record Integration of Predictive Analytics to Select High-Risk Stable Patients With Non-ST-Segment-Elevation Myocardial Infarction for Intensive Care Unit Admission.

    趋势排名:38 · 期刊:Circulation. Cardiovascular quality and outcomes · 类型:Journal Article · 语言:eng · PMID:33757310 · DOI:10.1161/CIRCOUTCOMES.120.007602

    最高第 3400:00 达到当日首次采集时已在榜04:16 观测离榜累计约4小时17分
  49. 49
    Integrative spatial profiling of 3D genome organization and gene expression in tissue.

    趋势排名:41 · 期刊:Cell · 类型:Journal Article · 语言:eng · PMID:42641604 · DOI:10.1016/j.cell.2026.07.039 · PMC:PMC13509204

    最高第 3500:00 达到当日首次采集时已在榜16:16 观测离榜累计约16小时17分
  50. 50
    Relationship between participation in leisure activities and the maintenance of successful aging in older Chinese adults: a 4-year longitudinal study.

    趋势排名:39 · 期刊:BMC geriatrics · 类型:Journal Article · 语言:eng · PMID:39623303 · DOI:10.1186/s12877-024-05574-1 · PMC:PMC11610103

    最高第 3618:56 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时45分