
PubMed · 实时热榜
- 01Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart disease in a Hong Kong Chinese population.
趋势排名:3 · 期刊:Diabetes research and clinical practice · 类型:Journal Article · 语言:eng · PMID:22515931 · DOI:10.1016/j.diabres.2012.03.012
最高第 1 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 02Objective monitoring tools for improved management of childhood asthma.
趋势排名:2 · 期刊:Respiratory research · 类型:Review · 语言:eng · PMID:38702779 · DOI:10.1186/s12931-024-02817-y · PMC:PMC11069259
最高第 1 名02:05 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 03Intraosseous calvarial haematoma mimicking a skull tumour in a child with Noonan syndrome: a case report.
趋势排名:1 · 期刊:Journal of surgical case reports · 类型:Journal Article · 语言:eng · PMID:42639270 · DOI:10.1093/jscr/rjag743 · PMC:PMC13502394
最高第 1 名22:08 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 04Prehospital epinephrine as a bridge to survival in traumatic cardiac arrest: A nationwide propensity score-matched analysis.
趋势排名:4 · 期刊:The American journal of emergency medicine · 类型:Journal Article · 语言:eng · PMID:42372567 · DOI:10.1016/j.ajem.2026.06.039
最高第 4 名17:04 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 05Global, regional, and national burden of HIV/AIDS, 1990-2023, with the estimated burden attributable to intimate partner violence and forecasted impacts of funding cuts through 2030: results from the Global Burden of Disease Study 2023.
趋势排名:18 · 期刊:The lancet. HIV · 类型:Journal Article · 语言:eng · PMID:42612664 · DOI:10.1016/S2352-3018(26)00147-5
最高第 4 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 06Postural Orthostatic Tachycardia Syndrome (POTS): A Review.
趋势排名:7 · 期刊:JAMA · 类型:Journal Article · 语言:eng · PMID:42635998 · DOI:10.1001/jama.2026.14809
最高第 4 名11:12 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 07Durvalumab and tremelimumab, with or without lenvatinib, combined with transarterial chemoembolisation in participants with embolisation-eligible hepatocellular carcinoma (EMERALD-3): a global, randomised, open-label, sponsor-blinded, phase 3 study.
趋势排名:6 · 期刊:The Lancet. Oncology · 类型:Randomized Controlled Trial · 语言:eng · PMID:42636832 · DOI:10.1016/S1470-2045(26)00278-0
最高第 4 名00:12 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 08Age-related differences in women's foot shape.
趋势排名:19 · 期刊:Maturitas · 类型:Journal Article · 语言:eng · PMID:27823747 · DOI:10.1016/j.maturitas.2016.09.001
最高第 5 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 09Neuroimaging Abnormalities and Genotype-Phenotype Correlations in Noonan Syndrome: A Multicenter Cohort Study.
趋势排名:5 · 期刊:The Journal of clinical endocrinology and metabolism · 类型:Journal Article · 语言:eng · PMID:42657773 · DOI:10.1210/clinem/dgag352
最高第 5 名19:12 达到19:12 首次观测上榜当日结束时仍在榜累计约4小时32分 - 10Baveno VIII - Advancing Consensus in Portal Hypertension.
趋势排名:32 · 期刊:Journal of hepatology · 类型:Review · 语言:eng · PMID:42624290 · DOI:10.1016/j.jhep.2026.07.030
最高第 6 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 11Anti-CD45RB monoclonal antibody-mediated transplantation tolerance.
趋势排名:33 · 期刊:Current molecular medicine · 类型:Review · 语言:eng · PMID:11899229 · DOI:10.2174/1566524013363348
最高第 7 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 12Discovery of 4H-Chromen-4-one Derivatives as a New Class of Selective Rho Kinase (ROCK) Inhibitors, which Showed Potent Activity in ex Vivo Diabetic Retinopathy Models.
趋势排名:9 · 期刊:Journal of medicinal chemistry · 类型:Journal Article · 语言:eng · PMID:31693351 · DOI:10.1021/acs.jmedchem.9b01143
最高第 7 名17:04 达到00:12 首次观测上榜当日结束时仍在榜累计约23小时32分 - 13Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2).
趋势排名:10 · 期刊:Bioorganic & medicinal chemistry · 类型:Journal Article · 语言:eng · PMID:26762835 · DOI:10.1016/j.bmc.2015.11.045 · PMC:PMC5947326
最高第 8 名17:04 达到00:12 首次观测上榜当日结束时仍在榜累计约23小时32分 - 14Evaluating sparsentan for the treatment of focal segmental glomerulosclerosis.
趋势排名:36 · 期刊:Expert opinion on pharmacotherapy · 类型:Review · 语言:eng · PMID:42622490 · DOI:10.1080/14656566.2026.2722324
最高第 8 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 15Ivonescimab plus chemotherapy versus placebo plus chemotherapy in patients with advanced EGFR-mutated non-small-cell lung cancer after disease progression on EGFR tyrosine kinase inhibitor therapy (HARMONi): a multicentre, randomised, double-blind, phase 3 trial.
趋势排名:13 · 期刊:The Lancet. Oncology · 类型:Randomized Controlled Trial · 语言:eng · PMID:42636833 · DOI:10.1016/S1470-2045(26)00282-2
最高第 8 名11:12 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 16Sex-specific aging clocks from a large-scale human phenome reveal distinct aging transitions and circulating signatures.
趋势排名:8 · 期刊:Nature aging · 类型:Journal Article · 语言:eng · PMID:42642518 · DOI:10.1038/s43587-026-01180-5
最高第 8 名22:08 达到02:05 首次观测上榜当日结束时仍在榜累计约21小时39分 - 17Novel quinazoline derivatives bearing various 6-benzamide moieties as highly selective and potent EGFR inhibitors.
趋势排名:11 · 期刊:Bioorganic & medicinal chemistry · 类型:Journal Article · 语言:eng · PMID:29523467 · DOI:10.1016/j.bmc.2018.02.022
最高第 9 名17:04 达到00:12 首次观测上榜当日结束时仍在榜累计约23小时32分 - 18Traumatic brain injury outcomes across human development index strata in 29 countries.
趋势排名:47 · 期刊:Nature medicine · 类型:Journal Article · 语言:eng · PMID:42618631 · DOI:10.1038/s41591-026-04600-6
最高第 9 名00:00 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 19Chemoradiotherapy versus short-course radiotherapy for response-adapted organ preservation in early-stage and intermediate-stage rectal cancer (STAR-TREC): 12-month results of an international, multicentre, open-label, parallel-group, randomised, phase 2/3 trial.
趋势排名:29 · 期刊:The Lancet. Oncology · 类型:Randomized Controlled Trial · 语言:eng · PMID:42633754 · DOI:10.1016/S1470-2045(26)00228-7
最高第 9 名00:12 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 20Liver resection after atezolizumab and bevacizumab versus maintenance therapy for locally advanced hepatocellular carcinoma (TALENTOP): a multicentre, open-label, randomised, phase 3 trial.
趋势排名:30 · 期刊:Lancet (London, England) · 类型:Randomized Controlled Trial · 语言:eng · PMID:42624156 · DOI:10.1016/S0140-6736(26)01252-3
最高第 11 名00:00 达到当日首次采集时已在榜17:04 观测离榜累计约17小时4分 - 21Childhood trauma and suicide ideation and attempts: Examining the mediating role of psychosocial, personality, lifestyle and biological factors.
趋势排名:14 · 期刊:Journal of affective disorders · 类型:Journal Article · 语言:eng · PMID:42637149 · DOI:10.1016/j.jad.2026.122414
最高第 11 名11:12 达到00:12 首次观测上榜当日结束时仍在榜累计约23小时32分 - 22Serum extracellular vesicles containing adenoviral E1A-DNA as a predictive biomarker for liquid biopsy in oncolytic adenovirus therapy.
趋势排名:34 · 期刊:Scientific reports · 类型:Journal Article · 语言:eng · PMID:41188286 · DOI:10.1038/s41598-025-22389-1 · PMC:PMC12586443
最高第 12 名00:00 达到当日首次采集时已在榜17:04 观测离榜累计约17小时4分 - 23Epidemiologic Study of Transfusion-Related Alpha-Gal Syndrome.
趋势排名:15 · 期刊:JAMA internal medicine · 类型:Journal Article · 语言:eng · PMID:42636004 · DOI:10.1001/jamainternmed.2026.3983 · PMC:PMC13504484
最高第 12 名11:12 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 24On-demand transarterial chemoembolisation combined with atezolizumab and bevacizumab in patients with untreated hepatocellular carcinoma (TALENTACE): a multicentre, randomised, open-label, phase 3 trial.
趋势排名:12 · 期刊:The lancet. Gastroenterology & hepatology · 类型:Journal Article · 语言:eng · PMID:42641632 · DOI:10.1016/S2468-1253(26)00212-8
最高第 12 名22:08 达到00:12 首次观测上榜当日结束时仍在榜累计约23小时32分 - 25Measuring the composition and availability of human resources for health by sex in 204 countries and territories, 1990-2023, and workforce gaps for universal health coverage: a systematic analysis for the Global Burden of Disease Study 2023.
趋势排名:37 · 期刊:The Lancet. Public health · 类型:Journal Article · 语言:eng · PMID:42612647 · DOI:10.1016/S2468-2667(26)00145-3 · PMC:PMC13501144
最高第 14 名00:00 达到当日首次采集时已在榜17:04 观测离榜累计约17小时4分 - 26Responders Vs. Non-Responders or How to Predict the Response to GLP-1 or GLP-1/GIP Receptor Agonist Therapy.
趋势排名:44 · 期刊:Diabetes, obesity & metabolism · 类型:Review · 语言:eng · PMID:42634284 · DOI:10.1111/dom.71226
最高第 14 名00:12 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 27DDIAS shields single-stranded DNA in mitosis and promotes vertebrate brain development.
趋势排名:17 · 期刊:Cell · 类型:Journal Article · 语言:eng · PMID:42636811 · DOI:10.1016/j.cell.2026.07.041
最高第 14 名11:12 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 28Effects of perceived treatment on quality of life and medical outcomes in a double-blind placebo surgery trial.
趋势排名:16 · 期刊:Archives of general psychiatry · 类型:Randomized Controlled Trial · 语言:eng · PMID:15066900 · DOI:10.1001/archpsyc.61.4.412
最高第 15 名17:04 达到17:04 首次观测上榜当日结束时仍在榜累计约6小时40分 - 29Longitudinal changes in sweet preferences in humans.
趋势排名:46 · 期刊:Physiology & behavior · 类型:Journal Article · 语言:eng · PMID:3588712 · DOI:10.1016/0031-9384(87)90166-1
最高第 15 名00:12 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 30Mendelian randomization study on the causal link between reproductive behavior and postpartum depression.
趋势排名:30 · 期刊:Medicine · 类型:Journal Article · 语言:eng · PMID:40958324 · DOI:10.1097/MD.0000000000044399 · PMC:PMC12440512
最高第 15 名00:00 达到当日首次采集时已在榜05:01 观测离榜累计约5小时1分 - 31Pancultural nostalgia in action: Prevalence, triggers, and psychological functions of nostalgia across cultures.
趋势排名:38 · 期刊:Journal of experimental psychology. General · 类型:Journal Article · 语言:eng · PMID:38252088 · DOI:10.1037/xge0001521
最高第 16 名00:00 达到当日首次采集时已在榜17:04 观测离榜累计约17小时4分 - 32Impact of ambient nitric oxide on device-dependent bias in fractional exhaled nitric oxide (FeNO) measurements and adjustment.
趋势排名:35 · 期刊:Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 类型:Journal Article · 语言:eng · PMID:42476304 · DOI:10.1016/j.anai.2026.07.010
最高第 17 名00:00 达到当日首次采集时已在榜05:01 观测离榜累计约5小时1分 - 33Diagnosis and management of acute hyperkalaemia.
趋势排名:43 · 期刊:BMJ (Clinical research ed.) · 类型:Review · 语言:eng · PMID:42629001 · DOI:10.1136/bmj-2026-100287
最高第 18 名00:00 达到当日首次采集时已在榜17:04 观测离榜累计约17小时4分 - 34TDP-43-Associated Neurodegenerative Disease Conceptualization and Integrated Staging: A Review.
趋势排名:22 · 期刊:JAMA neurology · 类型:Journal Article · 语言:eng · PMID:42636000 · DOI:10.1001/jamaneurol.2026.2812
最高第 18 名05:01 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 35COVID-19 mRNA or viral vector vaccine type and subject sex influence the SARS-CoV-2 T-cell response.
趋势排名:32 · 期刊:Vaccine · 类型:Journal Article · 语言:eng · PMID:40561567 · DOI:10.1016/j.vaccine.2025.127420 · PMC:PMC13116470
最高第 19 名00:12 达到00:12 首次观测上榜22:08 观测离榜累计约21小时56分 - 36Rigosertib Reverses Hypertrophic Cardiomyopathy in Noonan Syndrome.
趋势排名:39 · 期刊:Circulation · 类型:Journal Article · 语言:eng · PMID:42610277 · DOI:10.1161/CIRCULATIONAHA.126.080188 · PMC:PMC13496009
最高第 19 名00:00 达到当日首次采集时已在榜05:01 观测离榜累计约5小时1分 - 37Five-Year Outcomes of Perioperative Pembrolizumab for Early-Stage Non-Small-Cell Lung Cancer From the Randomized KEYNOTE-671 Study.
趋势排名:45 · 期刊:Annals of oncology : official journal of the European Society for Medical Oncology · 类型:Journal Article · 语言:eng · PMID:42628840 · DOI:10.1016/j.annonc.2026.08.005
最高第 20 名00:00 达到当日首次采集时已在榜17:04 观测离榜累计约17小时4分 - 38An inherited hypomorphic variant in PIEZO2 reveals structural features of mechanotransduction.
趋势排名:20 · 期刊:Neuron · 类型:Journal Article · 语言:eng · PMID:42636812 · DOI:10.1016/j.neuron.2026.07.030
最高第 20 名02:05 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 39A geroprotective probiotic and its functional metabolite counteract inflammaging to extend healthspan.
趋势排名:21 · 期刊:Nature aging · 类型:Journal Article · 语言:eng · PMID:42642521 · DOI:10.1038/s43587-026-01181-4
最高第 21 名22:08 达到05:01 首次观测上榜当日结束时仍在榜累计约18小时43分 - 40Eating Alone as Social Disengagement is Strongly Associated With Depressive Symptoms in Japanese Community-Dwelling Older Adults.
趋势排名:25 · 期刊:Journal of the American Medical Directors Association · 类型:Journal Article · 语言:eng · PMID:25687929 · DOI:10.1016/j.jamda.2015.01.078
最高第 23 名11:12 达到00:12 首次观测上榜当日结束时仍在榜累计约23小时32分 - 41Association of Easier Biologic Access with Remission and Other Clinical Outcomes in Severe Asthma: A Global Real-World Study.
趋势排名:23 · 期刊:Journal of asthma and allergy · 类型:Journal Article · 语言:eng · PMID:42638984 · DOI:10.2147/JAA.S597657 · PMC:PMC13501352
最高第 23 名22:08 达到00:12 首次观测上榜当日结束时仍在榜累计约23小时32分 - 42Case Report: A rare case of multi-vessel coronary artery-coronary sinus fistula combined with multiple coronary aneurysms initially presenting with frequent premature ventricular complexes.
趋势排名:27 · 期刊:Frontiers in cardiovascular medicine · 类型:Journal Article · 语言:eng · PMID:42643173 · DOI:10.3389/fcvm.2026.1920885 · PMC:PMC13503148
最高第 23 名02:05 达到当日首次采集时已在榜当日结束时仍在榜累计约23小时44分 - 43Elacestrant in Combination with Everolimus for Estrogen Receptor-Positive, HER2-Negative Previously Treated Advanced Breast Cancer: Results from ELEVATE.
趋势排名:34 · 期刊:Clinical cancer research : an official journal of the American Association for Cancer Research · 类型:Journal Article · 语言:eng · PMID:42635598 · DOI:10.1158/1078-0432.CCR-26-1816
最高第 24 名02:05 达到00:12 首次观测上榜当日结束时仍在榜累计约23小时32分 - 44Sustained benefit of adjuvant olaparib in women with germline BRCA1- and BRCA2- -associated high-risk HER2-negative early breast cancer: Updated results from the OlympiA phase III trial.
趋势排名:26 · 期刊:Annals of oncology : official journal of the European Society for Medical Oncology · 类型:Journal Article · 语言:eng · PMID:42636977 · DOI:10.1016/j.annonc.2026.08.002
最高第 24 名08:13 达到00:12 首次观测上榜当日结束时仍在榜累计约23小时32分 - 45Toward unified and comprehensive automated electroencephalogram interpretation: a multicentre development and validation of an electroencephalogram foundation model.
趋势排名:24 · 期刊:The Lancet. Digital health · 类型:Journal Article · 语言:eng · PMID:42642264 · DOI:10.1016/j.landig.2026.101039
最高第 24 名22:08 达到02:05 首次观测上榜当日结束时仍在榜累计约21小时39分 - 46Global and regional progress towards reduced burden of oral conditions between 2019 and 2023: a systematic analysis for the Global Burden of Disease Study 2023.
趋势排名:49 · 期刊:The Lancet. Public health · 类型:Journal Article · 语言:eng · PMID:42612648 · DOI:10.1016/S2468-2667(26)00143-X · PMC:PMC13501145
最高第 25 名00:00 达到当日首次采集时已在榜02:05 观测离榜累计约2小时5分 - 47Vaccination and Safe Living Strategies for Solid Organ Transplant Candidates and Recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice.
趋势排名:27 · 期刊:American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 类型:Journal Article · 语言:eng · PMID:42632426 · DOI:10.1016/j.ajt.2026.07.033
最高第 27 名00:00 达到当日首次采集时已在榜00:12 观测离榜累计约13分钟 - 48NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
趋势排名:28 · 期刊:ChemMedChem · 类型:Journal Article · 语言:eng · PMID:29928781 · DOI:10.1002/cmdc.201800398
最高第 28 名22:08 达到17:04 首次观测上榜当日结束时仍在榜累计约6小时40分 - 49Tracing the origins of de novo coronary collateral formation in cardiac repair.
趋势排名:29 · 期刊:Science (New York, N.Y.) · 类型:Journal Article · 语言:eng · PMID:42623479 · DOI:10.1126/science.ady3027
最高第 29 名00:00 达到当日首次采集时已在榜00:12 观测离榜累计约13分钟 - 50ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells.
趋势排名:30 · 期刊:European journal of medicinal chemistry · 类型:Journal Article · 语言:eng · PMID:30384048 · DOI:10.1016/j.ejmech.2018.10.052 · PMC:PMC7115410
最高第 30 名22:08 达到17:04 首次观测上榜当日结束时仍在榜累计约6小时40分



































