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  • 01
    Setting up an IPv6 only VM
    Too many applications are still using IPv4 only, which is a shame as IPv6 was standardised ~28 years ago. If you want to check if your application is IPv6 ready, best thing is to have a server or docker/podman network which is IPv6 only. I'm showing how to set up both variants here. Setting up RedHat 10 for IPv6 only Note Root access is, of course, required for all these commands. The following examples use eth0 network interface. Use nmcli con show to list down the network interfaces and adaptlaurencet
  • 02
    Running LM Studio Locally Doesn't Mean It Never Connects Out
    When we say “local LLM,” it is easy to mentally translate that into: Everything stays inside the PC. For inference, that can be true. But the application running the model is still an application with network-capable features. LM Studio, for example, may need connectivity for things such as: searching for models downloading models downloading runtimes checking for application updates It can also expose a local API server, connect to MCP servers, enable CORS, or serve the API to other devices onk-wada
  • 03
    Building Real-Time Analytics for a WhatsApp Native CRM
    Building Real-Time Analytics for a WhatsApp Native CRM Every CRM vendor ships a table of numbers. Very few ship analytics that a team actually acts on. When we were building the analytics layer inside Zetta CRM , the numbers were never the hard part — the hard part was deciding which numbers matter and getting them to the screen fast enough that a support lead can change their routing mid-shift, not report on last week's problems. This is the story of that layer: the event pipeline, the metric dIndra Gunanda
  • 04
    Stop Selling AI‑Sell The Outcome: Monetization Lessons For Indie Builders
    Lots of independent developers jump onto the AI trend, build a chat wrapper, and expect users to pay. Almost always, that approach fails. Users will not pay you just to access a large language model. They pay for the concrete outcome your tool delivers. Many early‑stage AI projects make the same mistake: they market the AI technology itself. They advertise “powerful LLM”, “smart AI agent”, and highlight model capabilities. But end users do not care which model runs under the hood. They care abouking li
  • 05
    GitHub Advanced Security ROI: Why Scanning Without SLAs Is a Waste of Money
    Git Hub Advanced Security ROI Why Scanning Without SLAs Is a Waste of Money Back to blog The Illusion of Security: Identification vs. Remediation Why Scanning Fails in a Vacuum: The Alert Fatigue Epidemic The Missing Link: Operationalizing Remediation Automated, contextual routing Intelligent grouping ("fix campaigns") Strict, severity-based SLA enforcement Pipeline enforcement and escalation Implementation: A Realistic Rollout Sequence Conclusion Sources GitHub Advanced Security ROI: Why ScanniInstaSLA
  • 06
    I fed a parody LinkedIn generator to three AI detectors. Gemini said it was human.
    There's a site called cringebot3000.com that generates deliberately terrible LinkedIn thought-leadership posts. You pick a topic and a cringe style ("The Vulnerability Post", "Proud to Announce"), it produces a story about a grandmother, a quirky German named Horst, or a cat that writes email subject lines. The footer says the posts are "guaranteed to make your followers shudder". It delivers. I maintain a small Claude skill called ai-tell-detector that audits drafts for the patterns that make tIlya Ploskovitov
  • 07
    React 20 `ref` as a Prop: Migrating Away From `forwardRef` Across a Large Component Library
    React 20 ref as a Prop: Migrating Away From forwardRef Across a Large Component Library This article was written with the assistance of AI, under human supervision and review. Most React component library maintenance debt stems from a single historical artifact: forwardRef . The pattern emerged because refs were special-cased in React's original architecture—passing them required wrapping every component that needed to expose a DOM handle. Component library teams spent years adding forwardRef wrjsmanifest
  • 08
    Regex Against a PDF: The One Endpoint That Skips OCR Entirely
    Most document pipelines have a reflex. A PDF comes in, and the first instinct is: run OCR, then parse it. That reflex costs time and money on documents that never needed it in the first place. Here's the distinction that gets skipped over. A PDF generated from Word, from an invoicing system, from a web page, from almost any modern software, is "born digital." Every character on the page is already stored as text, positioned and selectable, the same way this article's text is selectable in your bPDF4me
  • 09
    Stop Writing Regex to Match URLs — The Browser Already Can
    Priya was three paragraphs into rewriting a support ticket when the page flashed and her draft reverted to what it had looked like an hour earlier. She hadn't refreshed. Nobody had. The service worker had. It was running a cache-first strategy for ticket pages — fetch once, serve from cache after that, so the dashboard felt instant on a flaky connection. The intent was to cache /tickets/482 , the read-only view, and leave /tickets/482/edit alone, since an edit form is exactly the page you neverParsa Jiravand
  • 10
    Dashforge: an application orchestrator for React
    React solved rendering. Dashforge tries to solve orchestration — theming, forms, permissions, and visibility moved out of your components, declaratively, predictably, reusably. Two skins (MUI and Tailwind), one contract. Building complex applications isn't about building components. Inside a single module you're juggling forms, permissions, roles, visibility conditions, fields that depend on other fields, business logic. And all that logic ends up scattered across the app : a <Controller> here,kensaadi
  • 11
    1a vez trabalhando com git com time: tudo que você precisa saber
    Faz mais de 5 anos que eu não abria um PR ou issue técnica no Github, mas essa semana tenho aprendido algumas boas práticas e termos que reuni neste artigo. Introdução Essa semana eu fiz uma coisa simples: atualizei o README de um projeto open source, o 4noobs , da comunidade He4rt. Troquei um badge, ajustei o contraste de um logo, organizei umas pastas e adicionei um índice pra facilitar a navegação. Nada muito complexo no fim das contas. Só que antes de chegar no "nada muito complexo", eu passvitoriazzp
  • 12
    Vibe Coding vs Prompt-Driven: One Year Later, the Debate Is Already Outdated
    A year ago, the debate between “vibe coding” and “prompt-driven development” felt like the right lens for using AI in software. Today it’s outdated. The real frontier is no longer how to phrase a request, but how to build an environment that lets an AI agent explore, modify, and verify code safely. The shift from conversational prompts to structured development harnesses changes what it means to ship reliable software. Below are four concrete ways this evolution is reshaping daily work. From ProNicolas Dabene
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    redhat/granite-7b-lab-gguf
    排名:1 · 4-bit quantized version of model Granite-7b-lab · Red Hat, Inc. · 10K+ pulls · 5 stars · Updated almost 2 years agoRed Hat, Inc.
  • 021.0万
    redhat/granite-3-2b-instruct
    排名:2 · IBM's Granite 3.0 large language model (LLM), optimized for local large language model operations · Red Hat, Inc. · 10K+ pulls · 1 stars · Updated almost 2 years agoRed Hat, Inc.
  • 031.0万
    redhat/granite-3-1b-a400m-instruct
    排名:3 · IBM's Granite 3.0 large language model (LLM), optimized for local large language model operations · Red Hat, Inc. · 10K+ pulls · 8 stars · Updated almost 2 years agoRed Hat, Inc.
  • 041.0万
    redhat/granite-3-8b-instruct
    排名:4 · IBM's Granite 3.0 large language model (LLM), optimized for local large language model operations · Red Hat, Inc. · 10K+ pulls · 4 stars · Updated almost 2 years agoRed Hat, Inc.
  • 051.0万
    redhat/granite-3-3b-a800m-instruct
    排名:5 · IBM's Granite 3.0 large language model (LLM), optimized for local large language model operations · Red Hat, Inc. · 10K+ pulls · 1 stars · Updated almost 2 years agoRed Hat, Inc.
  • 061.0万
    redhat/granite-3.1-8b-instruct
    排名:6 · IBM's Granite 3.1 large language model (LLM), optimized for local large language model operations · Red Hat, Inc. · 10K+ pulls · 9 stars · Updated over 1 year agoRed Hat, Inc.
  • 071000.0万
    Python
    排名:7 · Python is an interpreted, interactive, object-oriented, open-source programming language. · Docker Hardened Image · 10M+ pulls · Updated about 10 hours agoDocker Hardened Image
  • 081000.0万
    Node.js
    排名:8 · Node.js is a JavaScript-based platform for server-side and networking applications. · Docker Hardened Image · 10M+ pulls · Updated about 4 hours agoDocker Hardened Image
  • 0910.0亿
    memcached
    排名:9 · Free & open source, high-performance, distributed memory object caching system. · Docker Official Image · 1B+ pulls · 2.5K stars · Updated 14 days agoDocker Official Image
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    nginx
    排名:10 · Official build of Nginx. · Docker Official Image · 1B+ pulls · 10K+ stars · Updated about 3 hours agoDocker Official Image
  • 1110.0亿
    busybox
    排名:11 · Busybox base image. · Docker Official Image · 1B+ pulls · 3.5K stars · Updated 18 days agoDocker Official Image
  • 1210.0亿
    alpine
    排名:12 · A minimal Docker image based on Alpine Linux with a complete package index and only 5 MB in size! · Docker Official Image · 1B+ pulls · 10K+ stars · Updated 8 days agoDocker Official Image
  • 1310.0亿
    postgres
    排名:13 · The PostgreSQL object-relational database system provides reliability and data integrity. · Docker Official Image · 1B+ pulls · 10K+ stars · Updated 3 days agoDocker Official Image
  • 1410.0亿
    redis
    排名:14 · Redis is the world’s fastest data platform for caching, vector search, and NoSQL databases. · Docker Official Image · 1B+ pulls · 10K+ stars · Updated 13 days agoDocker Official Image
  • 1510.0亿
    ubuntu
    排名:15 · Ubuntu is a Debian-based Linux operating system based on free software. · Docker Official Image · 1B+ pulls · 10K+ stars · Updated 34 minutes agoDocker Official Image
  • 1610.0亿
    python
    排名:16 · Python is an interpreted, interactive, object-oriented, open-source programming language. · Docker Official Image · 1B+ pulls · 10K+ stars · Updated 3 days agoDocker Official Image
  • 1710.0亿
    node
    排名:17 · Node.js is a JavaScript-based platform for server-side and networking applications. · Docker Official Image · 1B+ pulls · 10K+ stars · Updated 14 days agoDocker Official Image
  • 18500.0万
    Tomcat
    排名:18 · Apache Tomcat is an open source implementation of the Java Servlet and JavaServer Pages technologies · Docker Hardened Image · 5M+ pulls · Updated about 4 hours agoDocker Hardened Image
  • 19500.0万
    Eclipse Temurin
    排名:19 · The Eclipse Temurin project provides code and processes that support the building of runtime binaries and associated technologies that are high performance, enterprise-caliber, cross-platform, open-source licensed, and Java SE TCK-tested for general use across the Java ecosystem. · Docker Hardened Image · 5M+ pulls · Updated about 5 hours agoDocker Hardened Image
  • 2010.0亿
    mysql
    排名:20 · MySQL is a widely used, open-source relational database management system (RDBMS). · Docker Official Image · 1B+ pulls · 10K+ stars · Updated 23 days agoDocker Official Image
  • 2110.0亿
    mongo
    排名:21 · MongoDB document databases provide high availability and easy scalability. · Docker Official Image · 1B+ pulls · 10K+ stars · Updated 1 day agoDocker Official Image
  • 2210.0亿
    httpd
    排名:22 · The Apache HTTP Server Project · Docker Official Image · 1B+ pulls · 4.9K stars · Updated 14 days agoDocker Official Image
  • 23500.0万
    DHI Build
    排名:23 · Buildkit frontend for building Docker Hardened Images · Docker Hardened Image · 5M+ pulls · 1 stars · Updated about 5 hours agoDocker Hardened Image
  • 2410.0亿
    rabbitmq
    排名:24 · RabbitMQ is an open source multi-protocol messaging broker. · Docker Official Image · 1B+ pulls · 5.4K stars · Updated about 2 hours agoDocker Official Image
  • 2510.0亿
    docker
    排名:25 · Docker in Docker! (commonly known as "dind") · Docker Official Image · 1B+ pulls · 2.7K stars · Updated 7 days agoDocker Official Image
  • 2610.0亿
    traefik
    排名:26 · Traefik, The Cloud Native Edge Router · Docker Official Image · 1B+ pulls · 3.7K stars · Updated about 2 hours agoDocker Official Image
  • 2710.0亿
    hello-world
    排名:27 · Hello World! (an example of minimal Dockerization) · Docker Official Image · 1B+ pulls · 2.6K stars · Updated 7 days agoDocker Official Image
  • 2810.0亿
    mariadb
    排名:28 · MariaDB Server is a high performing open source relational database, forked from MySQL. · Docker Official Image · 1B+ pulls · 6.1K stars · Updated 1 day agoDocker Official Image
  • 29500.0万
    PostgreSQL
    排名:29 · The PostgreSQL object-relational database system provides reliability and data integrity. · Docker Hardened Image · 5M+ pulls · Updated about 4 hours agoDocker Hardened Image
  • 3010.0亿
    golang
    排名:30 · Go (golang) is a general purpose, higher-level, imperative programming language. · Docker Official Image · 1B+ pulls · 5.1K stars · Updated 13 minutes agoDocker Official Image
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  • 012771
    抄写员巴托比
    排名:1 · 评分:8.1 · [美] 赫尔曼·梅尔维尔 / 2026-4-1 / 陕西师范大学出版总社 / 32.00元 / 平装 · 小说 / 连续上榜4个月[美] 赫尔曼·梅尔维尔
  • 022807
    伊加利亚的女儿们
    排名:2 · 评分:9.2 · [挪] 格德·布兰腾伯格 / 2026-5 / 太白文艺出版社 / 68.00元 / 精装 · 小说 / 连续上榜2个月[挪] 格德·布兰腾伯格
  • 031093
    无论如何,潜水
    排名:3 · 评分:8.0 · 河美娜 / 2026-7 / 广西师大出版社 / 49.8 / 平装 · 文学河美娜
  • 041723
    永结无情游
    排名:4 · 评分:7.7 · 周嘉宁 / 2026-4 / 人民文学出版社 / 59 / 精装 · 小说 / 连续上榜3个月周嘉宁
  • 051192
    辞职上山:我在武当的200天
    排名:5 · 评分:8.2 · 李闯 / 2026-5 / 新星出版社 / 59.00元 / 平装 · 社会纪实 / 连续上榜3个月李闯
  • 06592
    另一个国度:在20世纪废墟上的漫游
    排名:6 · 评分:9.0 · 杨潇 / 2026-6 / 民主与建设出版社 / 88.00元 / 平装 · 文学 / 连续上榜2个月杨潇
  • 071447
    零诺
    排名:7 · 评分:9.3 · 行烟烟 / 2026-7-20 / 中信出版社 / 168 / 平装 · 小说行烟烟
  • 081023
    为父则刚
    排名:8 · 评分:9.0 · 杨雨坤 著 / 2026-6 / 广西师范大学出版社 / 52 / 平装 · 社会纪实 / 连续上榜2个月杨雨坤 著
  • 091733
    大厂小民:我在互联网公司的1480天
    排名:9 · 评分:8.3 · 张小满 / 2026-3 / 文汇出版社 / 59.00元 / 平装 · 社会纪实 / 连续上榜5个月张小满
  • 10352
    傍晚的邂逅
    排名:10 · 评分:8.7 · [韩]朴婉绪 / 2026-7 / 上海文艺出版社 / 58.00元 / 平装 · 小说[韩]朴婉绪
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    第二枪
    排名:11 · 评分:8.0 · [英] 安东尼·伯克莱 / 2026-6-30 / 北京联合出版公司 / 59.00元 / 平装 · 小说[英] 安东尼·伯克莱
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    爱的辛劳:一名心理咨询师见证的欲望、创伤与人间
    排名:12 · 评分:8.6 · [美] 斯蒂芬·格罗斯 / 2026-7 / 上海三联书店 / 49.00元 / 平装 · 社会纪实[美] 斯蒂芬·格罗斯
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    灵魂的肉身
    排名:13 · 评分:8.0 · [俄]柳德米拉·乌利茨卡娅 / 2026-5 / 译林出版社 / 58.00元 / 精装 · 小说 / 连续上榜2个月[俄]柳德米拉·乌利茨卡娅
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    翠鸟谋杀案
    排名:14 · 评分:8.1 · [英] 安东尼·霍洛维茨 / 2026-5 / 新星出版社 / 98.00元 / 平装 · 小说 / 连续上榜3个月[英] 安东尼·霍洛维茨
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    燃烧的龙舌兰:一个女人的墨西哥行记
    排名:15 · 评分:7.9 · 班卓 / 2026-3-31 / 上海人民出版社 / 72.00 / 平装 · 连续上榜4个月 / 文学班卓
  • 16405
    品味与阶层:漫画解读布尔迪厄的区分理论
    排名:16 · 评分:8.7 · [法] 蒂菲娜·里维埃尔 / 2026-6 / 广东人民出版社 / 98.00元 / 平装 · 绘本漫画[法] 蒂菲娜·里维埃尔
  • 17654
    给一个未出生孩子的信
    排名:17 · 评分:9.1 · [意] 奥丽娅娜·法拉奇 / 2026-5 / 九州出版社 / 66.00 / 精装 · 小说 / 连续上榜3个月[意] 奥丽娅娜·法拉奇
  • 18402
    双天至尊
    排名:18 · 评分:8.5 · 马家辉 / 2026-5 / 新星出版社 / 68.00元 / 平装 · 小说 / 连续上榜2个月马家辉
  • 19232
    肉与灵:当社会学家化身拳击手
    排名:19 · 评分:8.1 · [法] 洛伊克·华康德 / 2026-7 / 上海译文出版社 / 69.00元 / 平装 · 社会纪实[法] 洛伊克·华康德
  • 20197
    送你一颗子弹
    排名:20 · 评分:7.9 · 刘瑜 / 2026-5 / 民主与建设出版社 / 68.00 / 平装 · 文学刘瑜
Dwarkesh Patel
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  • 0120
    Mocktail
    排名:1 · Play Roblox on Linux · 分类:game · 近 30 天安装:3,441 · 趋势分:20.00 · 许可:Apache-2.0 · 开发者已验证Mocktail Project Authors
  • 0220
    VPN Unlimited
    排名:2 · Fast and private VPN with no traffic or speed limits · 分类:network · 近 30 天安装:1,559 · 趋势分:20.00 · 许可:LicenseRef-proprietary=https://www.keepsolid.com/eua · 开发者已验证KeepSolid, Inc.
  • 0320
    iDescriptor
    排名:3 · Manage and interact with Apple mobile devices (iPhone, iPad, iPod...) · 分类:utility · 近 30 天安装:741 · 趋势分:20.00 · 许可:AGPL-3.0-or-later · 开发者已验证iDescriptor Team
  • 0420
    Hardware Probe
    排名:4 · Check operability of computer hardware and find drivers · 分类:system · 近 30 天安装:595 · 趋势分:20.00 · 许可:BSD-2-Clause · 开发者已验证Linux Hardware Project
  • 0520
    PKVault
    排名:5 · Pokémon hub for your games · 分类:utility · 近 30 天安装:384 · 趋势分:20.00 · 许可:GPL-3.0-or-later · 开发者已验证Richard Haddad
  • 0620
    Lockpicker
    排名:6 · Recover passwords from their hash · 分类:utility · 近 30 天安装:1,230 · 趋势分:19.97 · 许可:GPL-3.0-or-later · 开发者已验证Sjoerd Stendahl
  • 0720
    USB Imager
    排名:7 · Write many USB drives at once · 分类:utility · 近 30 天安装:2,922 · 趋势分:19.93 · 许可:GPL-3.0-or-later · 开发者已验证Secu-Design®
  • 0820
    Voyager
    排名:8 · Browse and join online communities · 分类:network · 近 30 天安装:225 · 趋势分:19.91 · 许可:AGPL-3.0-only · 开发者已验证Alexander Harding
  • 0920
    Drift
    排名:9 · Edit and export videos easily · 分类:audiovideo · 近 30 天安装:2,932 · 趋势分:19.85 · 许可:GPL-3.0-or-later · 开发者已验证CutWire Studios
  • 1020
    Dippi
    排名:10 · Calculate display info like DPI · 分类:utility · 近 30 天安装:717 · 趋势分:19.74 · 许可:GPL-3.0-or-later · 开发者已验证Cassidy James Blaede
  • 1120
    Listen Moe
    排名:11 · J-POP and K-POP radio · 分类:audiovideo · 近 30 天安装:481 · 趋势分:19.68 · 许可:MIT · 开发者已验证noobping
  • 1220
    Hearts
    排名:12 · Play the classic Hearts card game · 分类:game · 近 30 天安装:218 · 趋势分:19.64 · 许可:MITRescator7
  • 1320
    mpz Music Player
    排名:13 · Play local music by folder · 分类:audiovideo · 近 30 天安装:581 · 趋势分:19.57 · 许可:GPL-3.0-or-later · 开发者已验证Oleg Antonyan
  • 1420
    Drawy
    排名:14 · Your handy, infinite brainstorming tool · 分类:graphics · 近 30 天安装:3,338 · 趋势分:19.57 · 许可:GPL-3.0-or-later · 开发者已验证KDE
  • 1519
    SemantiK
    排名:15 · Find the secret word · 分类:game · 近 30 天安装:353 · 趋势分:19.21 · 许可:GPL-3.0-or-later · 开发者已验证Krafting
  • 1618
    Ultimate Tic Tac Toe
    排名:16 · (Tic Tac Toe)² · 分类:game · 近 30 天安装:539 · 趋势分:18.39 · 许可:GPL-3.0-or-later · 开发者已验证Nokse
  • 1718
    Puzzled
    排名:17 · Solve various puzzles · 分类:game · 近 30 天安装:374 · 趋势分:18.17 · 许可:GPL-3.0-or-later · 开发者已验证Tilman Holube
  • 1818
    ScryLab
    排名:18 · Data analysis for engineers · 分类:development · 近 30 天安装:407 · 趋势分:17.99 · 许可:LicenseRef-proprietary=https://scrylab.de/terms-and-conditions/ · 开发者已验证Dominik Tirschler
  • 1918
    ClassIn
    排名:19 · One-stop interactive online classroom platform · 分类:education · 近 30 天安装:127 · 趋势分:17.62 · 许可:LicenseRef-proprietary=https://www.classin.com/agreement/Empower Education Online Ltd.
  • 2016
    Laser
    排名:20 · Rip CDs with ease · 分类:utility · 近 30 天安装:1,078 · 趋势分:16.15 · 许可:GPL-3.0-or-later · 开发者已验证Andreas Knoben
  • 2116
    Password Generator
    排名:21 · Create strong passwords in seconds · 分类:utility · 近 30 天安装:581 · 趋势分:16.11 · 许可:CC-BY-SA-4.0 · 开发者已验证Dr. Daniel Dumke
  • 2216
    muttum
    排名:22 · Guess a word in few attempts · 分类:game · 近 30 天安装:389 · 趋势分:15.89 · 许可:GPL-3.0-or-later · 开发者已验证Adrien Dorsaz
  • 2316
    Archives
    排名:23 · Create and view web archives · 分类:utility · 近 30 天安装:928 · 趋势分:15.86 · 许可:AGPL-3.0-only · 开发者已验证Evangelos "GeopJr" Paterakis
  • 2416
    Marknote
    排名:24 · Write down your thoughts · 分类:office · 近 30 天安装:1,510 · 趋势分:15.75 · 许可:GPL-2.0-or-later · 开发者已验证KDE
  • 2516
    GCLC
    排名:25 · Visualize and explore geometry · 分类:science · 近 30 天安装:94 · 趋势分:15.67 · 许可:MIT · 开发者已验证ADG Foundation
  • 2615
    Scratch
    排名:26 · Create stories, games, and animations, share with others around the world · 分类:development · 近 30 天安装:8,601 · 趋势分:15.04 · 许可:BSD-3-ClauseLifelong Kindergarten Group at the MIT Media Lab
  • 2715
    Mundi
    排名:27 · Learn geography · 分类:education · 近 30 天安装:1,338 · 趋势分:14.93 · 许可:GPL-3.0-or-later · 开发者已验证Ignacio Casal Quinteiro
  • 2815
    Ferdium
    排名:28 · Messenger for the desktop · 分类:network · 近 30 天安装:6,518 · 趋势分:14.91 · 许可:Apache-2.0 · 开发者已验证Ferdium Team
  • 2914
    Morse
    排名:29 · Learn Morse Code · 分类:education · 近 30 天安装:953 · 趋势分:14.11 · 许可:GPL-3.0-or-later · 开发者已验证Jaŭhien Lavonćjeŭ
  • 3014
    Hunt
    排名:30 · Find every word · 分类:game · 近 30 天安装:402 · 趋势分:13.81 · 许可:GPL-3.0-or-later · 开发者已验证Nathan Perlman
  • 3113
    Stencil
    排名:31 · Rename batches of files · 分类:utility · 近 30 天安装:717 · 趋势分:13.39 · 许可:GPL-3.0-or-later · 开发者已验证René Fouquet
  • 3213
    Timetable
    排名:32 · View your WebUntis timetable · 分类:education · 近 30 天安装:299 · 趋势分:13.24 · 许可:GPL-3.0-or-later · 开发者已验证Ostfriese4
  • 3313
    Siril
    排名:33 · Astronomical image processor · 分类:science · 近 30 天安装:1,419 · 趋势分:13.01 · 许可:GPL-3.0+ · 开发者已验证Free-astro Team
  • 3413
    Focal
    排名:34 · Organize tasks & notes in a tree. · 分类:utility · 近 30 天安装:231 · 趋势分:12.95 · 许可:LicenseRef-proprietary=https://focal.vargary.com/docs/TermsConditions.html · 开发者已验证Balázs János Varga
  • 3513
    Easy NATS
    排名:35 · Desktop GUI client for NATS and JetStream · 分类:development · 近 30 天安装:129 · 趋势分:12.53 · 许可:MIT · 开发者已验证mcthesw
  • 3612
    Eufonia Client
    排名:36 · Join Minecraft in-game events · 分类:game · 近 30 天安装:120 · 趋势分:11.73 · 许可:LicenseRef-proprietary · 开发者已验证Eufonia Studio S.A.
  • 3712
    Vinyl
    排名:37 · Elegant music player · 分类:audiovideo · 近 30 天安装:1,518 · 趋势分:11.51 · 许可:GPL-3.0-or-later · 开发者已验证M23Snezhok
  • 3811
    Ricochlime
    排名:38 · Satisfying monster shooter · 分类:game · 近 30 天安装:236 · 趋势分:11.41 · 许可:AGPL-3.0-only · 开发者已验证Adil Hanney
  • 3911
    GNU Octave
    排名:39 · Scientific Programming Language · 分类:education · 近 30 天安装:2,382 · 趋势分:11.03 · 许可:GPL-3.0+ · 开发者已验证John W. Eaton and others
  • 4011
    Mini Text
    排名:40 · Ephemeral scratch pad · 分类:utility · 近 30 天安装:417 · 趋势分:10.97 · 许可:GPL-3.0-or-later · 开发者已验证Nokse
  • 4111
    NouTube
    排名:41 · YouTube and YouTube Music in a single app · 分类:audiovideo · 近 30 天安装:5,635 · 趋势分:10.91 · 许可:AGPL-3.0-or-later · 开发者已验证Nonbili Inc.
  • 4211
    Zodia
    排名:42 · Natal charts, transits & synastry · 分类:network · 近 30 天安装:375 · 趋势分:10.78 · 许可:AGPL-3.0-or-later · 开发者已验证Bendik Aagaard Lynghaug
  • 4311
    Physics
    排名:43 · Prove Sir Isaac Newton correct · 分类:education · 近 30 天安装:227 · 趋势分:10.77 · 许可:GPL-3.0-or-laterSugar Labs Community
  • 4411
    Chaski
    排名:44 · A calmer way to read the web · 分类:network · 近 30 天安装:68 · 趋势分:10.58 · 许可:GPL-3.0-only · 开发者已验证a-chacon
  • 4510
    SSH Pilot
    排名:45 · Manage your servers with ease · 分类:utility · 近 30 天安装:2,642 · 趋势分:10.23 · 许可:GPL-3.0-or-later · 开发者已验证mFat
  • 4610
    ThinkOrSwim
    排名:46 · ThinkOrSwim Desktop application · 分类:office · 近 30 天安装:424 · 趋势分:10.08 · 许可:LicenseRef-proprietaryTD Ameritrade, Inc.
  • 4710
    SiYuan
    排名:47 · A privacy-first personal knowledge management system · 分类:utility · 近 30 天安装:467 · 趋势分:9.94 · 许可:AGPL-3.0SiYuan
  • 4810
    Emergency Alerts
    排名:48 · Receive emergency alerts · 分类:network · 近 30 天安装:241 · 趋势分:9.56 · 许可:GPL-3.0-or-later · 开发者已验证Leonhard
  • 499
    Plattenalbum
    排名:49 · Connect to your music · 分类:audiovideo · 近 30 天安装:506 · 趋势分:9.49 · 许可:GPL-3.0-or-later · 开发者已验证Martin Wagner
  • 509
    Maxint
    排名:50 · True financial clarity. · 分类:office · 近 30 天安装:260 · 趋势分:9.45 · 许可:LicenseRef-proprietary · 开发者已验证Maxint
freeCodeCamp
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  • 01
    Mitochondrial–neuroimmune interfaces in post-stroke spasticity: from acute brain injury to chronic motor phenotypes
    Post-stroke spasticity is a common and clinically consequential manifestation of the upper motor neuron syndrome, yet its mechanisms are incompletely explained by stretch reflex hyperexcitability alone. Established models emphasize corticospinal and corticoreticulospinal injury, altered brainstem descending drive, spinal reflex amplification, impaired inhibitory control, and secondary changes in skeletal muscle and connective tissue. In parallel, stroke induces profound mitochondrial stress andZihang Huang
  • 02
    FIS1 dependent peripheral fission exacerbates mitochondrial fragmentation and dysfunction in prion diseases
    IntroductionMitochondrial dysfunction is an early and critical feature of neuronal injury in prion diseases, a group of fatal transmissible neurodegenerative disorders. Mitochondrial dynamics, a core component of mitochondrial quality control, maintains neuronal homeostasis through balanced fission and fusion. Although mitochondrial fission can be further divided into distinct spatial subtypes, the specific subtype involved in prion-associated neurotoxicity and its regulatory mechanisms remain uFengting Gou
  • 03
    Cellular senescence and senolytic therapy in traumatic brain injury
    Traumatic brain injury (TBI) is a major cause of death and long-term disability in the United States. The initial primary injury in TBI is followed by a secondary injury cascade of molecular events, which can persist for years, and contributes to neuroinflammation, neurodegeneration, and long-term functional deficits after TBI. In this review, we will discuss evidence that cellular senescence in TBI, where damaged cells enter a state of permanent cell-cycle arrest and release pro-inflammatory faDarrell W. Brann
  • 04
    Cerebrospinal fluid biomarkers in E200K genetic Creutzfeldt–Jakob disease: a national study from an endemic Slovak cohort
    BackgroundGenetic Creutzfeldt–Jakob disease (gCJD) is a rare inherited prion disorder caused by pathogenic variants in the PRNP gene. Slovakia represents one of the major endemic regions worldwide, with most genetic cases linked to the E200K variant. Reliable cerebrospinal fluid (CSF) biomarkers remain important for diagnosis and surveillance in this setting.MethodsWe analyzed CSF samples from 77 consecutive symptomatic patients with genetically confirmed E200K gCJD referred to the National RefeDana Zakova
  • 05
    Elevated cerebral blood flow in distal and intermediate arterial territories in pediatric sickle cell anemia
    IntroductionChildren with sickle cell anemia (SCA) are at increased risk of cerebrovascular complications due to chronic anemia and progressive vascular injury, yet how their cerebral hemodynamics are altered remains poorly understood. Previous research has shown that overall cerebral blood flow (CBF) is often higher in SCA, likely as an adaptive response to their chronic anemia, while this CBF increase is also linked to a greater risk of stroke, silent infarcts, and cognitive deficits. DistinguPing Zou Stinnett
  • 06
    Structural changes in gray matter and white matter across the Alzheimer’s disease continuum
    ObjectiveThe pathophysiological spectrum of Alzheimer’s disease (AD) is a continuum, with the AT(N) framework defining stages based on the presence of Aβ pathology, tau pathology, and neurodegeneration. However, the spatial characteristics of gray matter (GM) and white matter (WM) changes at different stages remain insufficiently defined. This study aimed to establish a cross-sectional cohort of the AD continuum using the AT(N) staging system and systematically delineate the spatial features ofShuai Lin
  • 07
    Age-associated differences in cervical sagittal alignment parameters among asymptomatic adults: a cross-sectional reference study
    PurposeWhile age-adjusted alignment goals are established for the lumbar spine, analogous clinically actionable tools are lacking for cervical sagittal assessment. This study aimed to derive and internally assess simple, age- and sex-specific formulas for key cervical parameters—thoracic inlet angle minus cervical lordosis (TIA-CL), neck tilt (NT), and cervical sagittal vertical axis (cSVA)—in asymptomatic adults.MethodsThis retrospective cross-sectional study analyzed 632 rigorously screened asYu Zhang
  • 08
  • 09
    A perspective on the use of the CatWalk device to assess dynamic spasticity in rodent models
    IntroductionSpasticity is a hallmark of upper motor neuron syndrome and arises from complex neurophysiological and biomechanical alterations, including disinhibition of the stretch reflex and secondary changes in muscle properties. While rodent models are widely used to study spasticity, objective assessment of dynamic spasticity during locomotion remains challenging. The CatWalk (CW) system is a well-established tool for automated gait analysis; however, its specific utility in quantifying spasJohannes C. Heinzel
  • 10
    Efficacy of transcranial direct current stimulation for disorders of consciousness: an updated systematic review and meta-analysis based on sham-controlled randomized trials
    BackgroundTranscranial direct current stimulation (tDCS) may improve behavioral signs of consciousness in patients with disorders of consciousness (DoC), but evidence from randomized controlled trials (RCTs) and previous meta-analyses has remained inconsistent. We evaluated the efficacy and safety of tDCS in patients with DoC and explored potential effect modifiers.MethodsPubMed, Embase, Scopus, Web of Science, and the Cochrane Library were searched for RCTs comparing active tDCS with sham stimuFuqiang Wang
  • 11
    Effects of acupuncture on mild cognitive impairment via the microbiota–gut–brain axis: a systematic review
    BackgroundMild Cognitive Impairment (MCI) is a critical window for intervention in neurodegenerative diseases. As emerging evidence suggests the role of microbiota–gut–brain (MGB) axis on cognitive health, this systematic review aims to evaluate the efficacy and underlying mechanisms of acupuncture in modulating the MGB axis to alleviate cognitive decline.MethodsA systematic search was conducted across PubMed/MEDLINE, Web of Science, Scopus, and Cochrane CENTRAL from inception to April 2026. FolMona Sadat Khalifeh Soltani
  • 12
    Graphomotor performance as a quantitative marker of Alzheimer’s disease: a tablet-based case–control ROC study
    BackgroundFrom the clinical and neurobiological perspective of cortico subcortical loop concepts, Alzheimer’s disease (AD) is associated with progressive deterioration of cognitive, emotional, and motor functions, which can be assessed subclinically using digital motion tracking technology in an electromagnetic digitizing tablet technology. Graphomotor analysis provides a source of sensitive digital biomarkers with potential applications in the early diagnosis and monitoring of AD.MethodsA case–Edward Jacek Gorzelańczyk
  • 13
    Localizing the epileptogenic zone in drug-resistant epilepsy based on ictal SEEG high-resolution time-frequency representation
    IntroductionDrug-resistant epilepsy (DRE) presents a critical clinical challenge, and accurate epileptogenic zone (EZ) localization is essential for successful surgical intervention. Stereoelectroencephalography (SEEG) is widely applied in clinical practice, but conventional visual inspection and high-frequency oscillations (HFOs) suffer from low efficiency, poor reproducibility, and insufficient representation of complex neural dynamics, failing to improve postsurgical seizure-free rates substaGenyu Fu
  • 14
    Electromyographic responses of the auriculomotor system during effortful listening in hearing aid users
    BackgroundAuricular muscles in humans may still display increased activity associated with auditory attention and effortful listening in complex patterns. As research into this auriculomotor system has primarily been conducted in normal-hearing participants, this study investigated electromyographic (EMG) signals of auricular muscles in hearing aid users under challenging listening conditions in order to evaluate their potential future use as a measure of perceived listening effort.MethodsTwentyAndreas Schroeer
  • 15
    Quantitative electroencephalography as a next-generation tool in neurodiagnostics: significance, clinical applications, and practical interpretative frameworks
    Introduction and objectiveThis article provides a comprehensive review of the methodology of Quantitative Electroencephalography (QEEG) as an advanced tool in modern neurodiagnostics. The objective of this study is to systematize knowledge regarding the technical aspects of signal acquisition, its specific clinical applications, and the interpretative frameworks that determine the efficacy of personalized therapeutic interventions in psychiatry and neurology.Materials and methodsThis paper constMarta Kopańska
  • 16
    A single-cell transcriptomic atlas of the periventricular proliferative zone in the late gestation fetal brain in the pigtail macaque
    BackgroundThe fetal brain undergoes rapid cellular and structural changes in late gestation, when waves of neurogenesis and gliogenesis shape cortical circuitry. The ventricular zone (VZ), subventricular zone (SVZ), periventricular white matter (PVWM), and deep white matter (DWM) are enriched in neuroprogenitor cells, newborn neurons, and interneurons, which are regions challenging to study in the third-trimester human fetal brain. The nonhuman primate (NHP) provides a powerful translational modJohn A. Cornelius
  • 17
    Molecules, meaning, and physiology: disentangling the active ingredients of psychedelic therapeutics
    Psychedelic-assisted therapy has shown rapid and durable benefits across multiple psychiatric conditions, yet the mechanisms underlying these effects remain incompletely understood. Full-dose psychedelic sessions simultaneously engage serotonergic neurochemistry, high-intensity subjective experience, and autonomic-interoceptive physiology, making it difficult to determine which components are necessary or sufficient for therapeutic change. This perspective proposes that three partially separableKim P. C. Kuypers
  • 18
    A user-friendly graphical user interface for paw touch classification in rodent cylinder testing
    In unilateral rodent models of disease or injury, deficits are induced in only one side of the body, allowing the difference in right versus left limb usage to serve as a metric of disease/injury severity and recovery with various treatments. Unilateral rat models are commonly used for conditions such as Parkinson’s disease (via the neurotoxin 6-hydroxydopamine, 6-OHDA), stroke, and traumatic brain injury, as well as cervical spinal cord injury and peripheral nerve damage. The ‘cylinder test’ haTyler R. Johnson
  • 19
    Exploring the differences in neural oscillation mechanisms before and after sleep deprivation
    IntroductionSleep deprivation is widespread in modern society and can impair cognitive function and behavioral performance. However, the neural changes associated with individual differences in vulnerability to sleep loss remain unclear, particularly whether temporal fluctuations in neural oscillations provide information beyond conventional mean spectral measures.MethodsWe analyzed a publicly available resting-state electroencephalogram (EEG) dataset comprising 64 participants assessed under noZitong Cui
  • 20
    Reactive-accelerated-aging soak testing of thin-film polyimide layers treated with an oxygen plasma and chemical soaking
    Reliable bonding between polyimide layers is critical for the long-term performance of thin-film neural interfaces, yet the long-term durability of common adhesion methods under physiologically relevant conditions remains unclear. This study uses reactive-accelerated-aging (RAA) soak testing at 87°C to compare the ability of surface treatments based on oxygen plasma and KOH/HCl soaks to enhance polyimide-to-polyimide adhesion. Peel testing was performed as a function of soak time and strip widthKenneth A. Fluker